Histochemical changes in intestinal atresia and its implications on surgical management: A preliminary report
Histochemical studies of the intestine were performed on five neonates, three with intestinal atresia and two as normal controls. In this preliminary report, changes secondary to ischemia and obstruction were defined. It was shown that the ischemic changes were limited in extent both proximally and...
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| Veröffentlicht in: | Journal of pediatric surgery 1986, Vol.21 (1), p.17-21 |
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| container_title | Journal of pediatric surgery |
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| creator | Hamdy, M.H. Man, D.W.K. Bain, D. Kirkland, I.S. |
| description | Histochemical studies of the intestine were performed on five neonates, three with intestinal atresia and two as normal controls. In this preliminary report, changes secondary to ischemia and obstruction were defined. It was shown that the ischemic changes were limited in extent both proximally and distally, and the obstructive changes were reversible. A conservative approach to resection in the management of intestinal atresia is suggested. Limited resection of the dilated proximal bowel together with the use of total parenteral nutrition will allow for a safe waiting period for the pathological changes to reverse themselves and effective peristalsis to return. |
| doi_str_mv | 10.1016/S0022-3468(86)80643-1 |
| format | Article |
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In this preliminary report, changes secondary to ischemia and obstruction were defined. It was shown that the ischemic changes were limited in extent both proximally and distally, and the obstructive changes were reversible. A conservative approach to resection in the management of intestinal atresia is suggested. Limited resection of the dilated proximal bowel together with the use of total parenteral nutrition will allow for a safe waiting period for the pathological changes to reverse themselves and effective peristalsis to return.</description><identifier>ISSN: 0022-3468</identifier><identifier>EISSN: 1531-5037</identifier><identifier>DOI: 10.1016/S0022-3468(86)80643-1</identifier><identifier>PMID: 3944751</identifier><identifier>CODEN: JPDSA3</identifier><language>eng</language><publisher>Philadelphia, PA: Elsevier Inc</publisher><subject>Acetylcholinesterase - metabolism ; Biological and medical sciences ; Biopsy ; Cholinergic Fibers - pathology ; Colon - abnormalities ; Colon - pathology ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastrointestinal Motility ; Humans ; Infant, Newborn ; Intestinal atresia ; Intestinal Atresia - pathology ; Intestinal Atresia - surgery ; Intestine, Large - innervation ; Intestine, Small - abnormalities ; Intestine, Small - innervation ; Intestine, Small - pathology ; Male ; Malformations ; Medical sciences ; Rectum - abnormalities ; Rectum - pathology ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><ispartof>Journal of pediatric surgery, 1986, Vol.21 (1), p.17-21</ispartof><rights>1986 Grune & Stratton, Inc. 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In this preliminary report, changes secondary to ischemia and obstruction were defined. It was shown that the ischemic changes were limited in extent both proximally and distally, and the obstructive changes were reversible. A conservative approach to resection in the management of intestinal atresia is suggested. Limited resection of the dilated proximal bowel together with the use of total parenteral nutrition will allow for a safe waiting period for the pathological changes to reverse themselves and effective peristalsis to return.</description><subject>Acetylcholinesterase - metabolism</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Cholinergic Fibers - pathology</subject><subject>Colon - abnormalities</subject><subject>Colon - pathology</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastrointestinal Motility</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Intestinal atresia</subject><subject>Intestinal Atresia - pathology</subject><subject>Intestinal Atresia - surgery</subject><subject>Intestine, Large - innervation</subject><subject>Intestine, Small - abnormalities</subject><subject>Intestine, Small - innervation</subject><subject>Intestine, Small - pathology</subject><subject>Male</subject><subject>Malformations</subject><subject>Medical sciences</subject><subject>Rectum - abnormalities</subject><subject>Rectum - pathology</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. 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Liver. Pancreas. Abdomen</topic><topic>Gastrointestinal Motility</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Intestinal atresia</topic><topic>Intestinal Atresia - pathology</topic><topic>Intestinal Atresia - surgery</topic><topic>Intestine, Large - innervation</topic><topic>Intestine, Small - abnormalities</topic><topic>Intestine, Small - innervation</topic><topic>Intestine, Small - pathology</topic><topic>Male</topic><topic>Malformations</topic><topic>Medical sciences</topic><topic>Rectum - abnormalities</topic><topic>Rectum - pathology</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hamdy, M.H.</creatorcontrib><creatorcontrib>Man, D.W.K.</creatorcontrib><creatorcontrib>Bain, D.</creatorcontrib><creatorcontrib>Kirkland, I.S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pediatric surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hamdy, M.H.</au><au>Man, D.W.K.</au><au>Bain, D.</au><au>Kirkland, I.S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Histochemical changes in intestinal atresia and its implications on surgical management: A preliminary report</atitle><jtitle>Journal of pediatric surgery</jtitle><addtitle>J Pediatr Surg</addtitle><date>1986</date><risdate>1986</risdate><volume>21</volume><issue>1</issue><spage>17</spage><epage>21</epage><pages>17-21</pages><issn>0022-3468</issn><eissn>1531-5037</eissn><coden>JPDSA3</coden><abstract>Histochemical studies of the intestine were performed on five neonates, three with intestinal atresia and two as normal controls. In this preliminary report, changes secondary to ischemia and obstruction were defined. It was shown that the ischemic changes were limited in extent both proximally and distally, and the obstructive changes were reversible. A conservative approach to resection in the management of intestinal atresia is suggested. Limited resection of the dilated proximal bowel together with the use of total parenteral nutrition will allow for a safe waiting period for the pathological changes to reverse themselves and effective peristalsis to return.</abstract><cop>Philadelphia, PA</cop><pub>Elsevier Inc</pub><pmid>3944751</pmid><doi>10.1016/S0022-3468(86)80643-1</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3468 |
| ispartof | Journal of pediatric surgery, 1986, Vol.21 (1), p.17-21 |
| issn | 0022-3468 1531-5037 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Acetylcholinesterase - metabolism Biological and medical sciences Biopsy Cholinergic Fibers - pathology Colon - abnormalities Colon - pathology Female Gastroenterology. Liver. Pancreas. Abdomen Gastrointestinal Motility Humans Infant, Newborn Intestinal atresia Intestinal Atresia - pathology Intestinal Atresia - surgery Intestine, Large - innervation Intestine, Small - abnormalities Intestine, Small - innervation Intestine, Small - pathology Male Malformations Medical sciences Rectum - abnormalities Rectum - pathology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus |
| title | Histochemical changes in intestinal atresia and its implications on surgical management: A preliminary report |
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