Efficacy Of Topical Amoxicillin Plus Clavulanate/Ticarcillin Plus Clavulanate And Clindamycin In Contaminated Head And Neck Surgery: Effect Of Antibiotic Spectra And Duration Of Therapy

This prospective, randomized trial was designed to determine the efficacy and mechanism of action of topical mouthwash versus parenterally administered perioperative prophylactic antibiotics in contaminated head and neck surgery. Patients were randomly assigned to 1 of 4 treatment groups: 1 day of p...

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Veröffentlicht in:	The Journal of infectious diseases 1994-09, Vol.170 (3), p.729-732
Hauptverfasser:	Grandis, Jennifer Rubin, Vickers, Richard M., Rihs, John D., Yu, Victor L., Johnson, Jonas T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amoxicillin - administration & dosage Amoxicillin - therapeutic use Anti-Bacterial Agents - therapeutic use Antibiotic prophylaxis Antibiotics Bacteria Carcinoma, Squamous Cell - surgery Clavulanic Acid Clavulanic Acids - administration & dosage Clavulanic Acids - therapeutic use Concise Communications Cultural groups Drug Administration Schedule Drug Therapy, Combination - therapeutic use Gram-Negative Aerobic Bacteria - isolation & purification Head Head and Neck Neoplasms - surgery Health care administration Humans Laryngeal Neoplasms - surgery Mouth Mouthwashes Neck Prospective Studies Surgical Wound Infection - prevention & control Ticarcillin - administration & dosage Ticarcillin - therapeutic use Wound infections
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