Inhibition of Macrophage Chemotaxis and Peripheral Nerve Regeneration in Normal and Hyperglycemic Rats by the Aldose Reductase Inhibitor Tolrestat

This study examined the effect of Tolrestat, an inhibitor of aldose reductase, on the regenerative capacity and macrophage chemotactic property of crush-injured sciatic nerve in normal and galactose-fed rats. Galactose intoxication reduced the incidence of regeneration but did not alter the regenera...

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