Mucosal destruction and regeneration of the colon by local hyperthermia. An experimental preliminary study

Mucosal destruction and regeneration of the colon by local hyperthermia. An experimental preliminary study

An experimental model has been developed to produce colonic mucosal destruction followed by regeneration. The canine model consists of a defunctioned portion of the large intestine which has been subjected to water at a temperature of 125 degrees F for 7 hours. Colonic specimens were harvested at di...

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Veröffentlicht in:Diseases of the colon & rectum 1986-03, Vol.29 (3), p.177-181
Hauptverfasser: Ger, R, Ravo, B, Harris, M, Waxman, M, Addei, K A
Format: Artikel
Sprache:eng
Schlagworte:
Absorption
Animals
Colon - growth & development
Colon - metabolism
Colonic Diseases - etiology
Colonic Diseases - pathology
Dogs
Hot Temperature
Mucous Membrane - metabolism
Necrosis
Xylose - metabolism
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container_end_page 181
container_issue 3
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container_title Diseases of the colon & rectum
container_volume 29
creator Ger, R
Ravo, B
Harris, M
Waxman, M
Addei, K A
description An experimental model has been developed to produce colonic mucosal destruction followed by regeneration. The canine model consists of a defunctioned portion of the large intestine which has been subjected to water at a temperature of 125 degrees F for 7 hours. Colonic specimens were harvested at different periods of up to six weeks and studied macro- and microscopically. It has been shown that it is possible to achieve significant mucosal destruction and regeneration. Possible adaptation to clinical states is presented and discussed.
doi_str_mv 10.1007/BF02555018
format Article
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identifier ISSN: 0012-3706
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source MEDLINE; SpringerLink Journals; Journals@Ovid Complete
subjects Absorption
Animals
Colon - growth & development
Colon - metabolism
Colonic Diseases - etiology
Colonic Diseases - pathology
Dogs
Hot Temperature
Mucous Membrane - metabolism
Necrosis
Xylose - metabolism
title Mucosal destruction and regeneration of the colon by local hyperthermia. An experimental preliminary study
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