Abnormal erythrocyte and lymphocyte chemiluminescence in chronic granulomatous disease: Evidence for a generalized membrane defect

Concanavalin A (soluble)- and/or opsonized zymosan (particulate)-stimulated luminol-dependent chemiluminescence was demonstrated in normal human lymphocytes, erythrocytes, and in the membrane (ghost) fractions of polymorphonuclear neutrophils and erythrocytes. By contrast, seven patients with chroni...

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Veröffentlicht in:	Clinical immunology and immunopathology 1986, Vol.38 (1), p.1-12
Hauptverfasser:	Peerless, Allen G., Stiehm, E.Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Biological and medical sciences blood cells chemiluminescence Child Child, Preschool chronic granulomatous disease Cytotoxicity, Immunologic Erythrocyte Membrane - metabolism erythrocytes Female Granulomatous Disease, Chronic - blood Hematologic and hematopoietic diseases Humans Infant Luminescent Measurements Luminol - pharmacology lymphocytes Lymphocytes - metabolism Male man Medical sciences membranes NADH, NADPH Oxidoreductases - analysis NADPH Oxidases Neutrophils - metabolism Other diseases. Hematologic involvement in other diseases Zymosan - pharmacology
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