Inflow versus deoxyhemoglobin effects in bold functional MRI using gradient echoes at 1.5 T

Modified gradient‐echo MR techniques were applied to study the effects of inflow on functional brain imaging studies using visual and motor cortex stimulation. The results demonstrate that the large signal changes, seen in previously reported gradient‐echo studies at 1.5–2.0 T, are dominated by dire...

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Veröffentlicht in:NMR in biomedicine 1994-03, Vol.7 (1-2), p.83-88
Hauptverfasser: Duyn, Jeff H., Moonen, Chrit T. W., van Yperen, Gert H., de Boer, Ruud W., Luyten, Peter R.
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container_end_page 88
container_issue 1-2
container_start_page 83
container_title NMR in biomedicine
container_volume 7
creator Duyn, Jeff H.
Moonen, Chrit T. W.
van Yperen, Gert H.
de Boer, Ruud W.
Luyten, Peter R.
description Modified gradient‐echo MR techniques were applied to study the effects of inflow on functional brain imaging studies using visual and motor cortex stimulation. The results demonstrate that the large signal changes, seen in previously reported gradient‐echo studies at 1.5–2.0 T, are dominated by direct inflow effects, in particular when using a large flip angle and a thin slice. The findings suggest that inflow‐based functional imaging, along with Blood Oxygenation Level Dependent (BOLD) functional MRI, may play an important role in future research towards the functional organization of the human brain.
doi_str_mv 10.1002/nbm.1940070113
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subjects Angiography - methods
Hemoglobins - analysis
Humans
Image Enhancement - methods
Magnetic Resonance Imaging - methods
Motor Cortex - anatomy & histology
Motor Cortex - blood supply
Motor Cortex - physiology
Oxygen - blood
Visual Cortex - anatomy & histology
Visual Cortex - blood supply
Visual Cortex - physiology
title Inflow versus deoxyhemoglobin effects in bold functional MRI using gradient echoes at 1.5 T
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