Inflow versus deoxyhemoglobin effects in bold functional MRI using gradient echoes at 1.5 T
Modified gradient‐echo MR techniques were applied to study the effects of inflow on functional brain imaging studies using visual and motor cortex stimulation. The results demonstrate that the large signal changes, seen in previously reported gradient‐echo studies at 1.5–2.0 T, are dominated by dire...
Gespeichert in:
Veröffentlicht in: | NMR in biomedicine 1994-03, Vol.7 (1-2), p.83-88 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 88 |
---|---|
container_issue | 1-2 |
container_start_page | 83 |
container_title | NMR in biomedicine |
container_volume | 7 |
creator | Duyn, Jeff H. Moonen, Chrit T. W. van Yperen, Gert H. de Boer, Ruud W. Luyten, Peter R. |
description | Modified gradient‐echo MR techniques were applied to study the effects of inflow on functional brain imaging studies using visual and motor cortex stimulation. The results demonstrate that the large signal changes, seen in previously reported gradient‐echo studies at 1.5–2.0 T, are dominated by direct inflow effects, in particular when using a large flip angle and a thin slice. The findings suggest that inflow‐based functional imaging, along with Blood Oxygenation Level Dependent (BOLD) functional MRI, may play an important role in future research towards the functional organization of the human brain. |
doi_str_mv | 10.1002/nbm.1940070113 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76679114</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>76679114</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3783-df08704b86d6345033b0a4d96efe52a06eff63b7df225a75553341a471af02cf3</originalsourceid><addsrcrecordid>eNqFkEtLxDAUhYMoOj627oSs3HW8eTXtUsXH4AsGRdBFSNubsdo22rTq_HsrMyiuXJ0L95xv8RGyy2DMAPhBk9VjlkoADYyJFTJikKYRkylfJSNIFY-ETGCDbIbwDACJFHydrCcQJ0rAiDxOGlf5D_qObegDLdB_zp-w9rPKZ2VD0TnMu0CHM_NVQV3f5F3pG1vRq-mE9qFsZnTW2qLEpqOYP3kM1HaUjRW93SZrzlYBd5a5Re5OT26Pz6PLm7PJ8eFllAudiKhwkGiQWRIXsZAKhMjAyiKN0aHiFoZ0sch04ThXViulhJDMSs2sA547sUX2F9zX1r_1GDpTlyHHqrIN-j4YHcc6ZUwOxfGimLc-hBadeW3L2rZzw8B82zSDTfNrcxjsLcl9VmPxU1_qG_7p4v9RVjj_h2auj67-sKPFtgwdfv5sbftiYi20MvfXZwaOHuT0YsrNhfgCTYeO_g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>76679114</pqid></control><display><type>article</type><title>Inflow versus deoxyhemoglobin effects in bold functional MRI using gradient echoes at 1.5 T</title><source>MEDLINE</source><source>Wiley Journals</source><creator>Duyn, Jeff H. ; Moonen, Chrit T. W. ; van Yperen, Gert H. ; de Boer, Ruud W. ; Luyten, Peter R.</creator><creatorcontrib>Duyn, Jeff H. ; Moonen, Chrit T. W. ; van Yperen, Gert H. ; de Boer, Ruud W. ; Luyten, Peter R.</creatorcontrib><description>Modified gradient‐echo MR techniques were applied to study the effects of inflow on functional brain imaging studies using visual and motor cortex stimulation. The results demonstrate that the large signal changes, seen in previously reported gradient‐echo studies at 1.5–2.0 T, are dominated by direct inflow effects, in particular when using a large flip angle and a thin slice. The findings suggest that inflow‐based functional imaging, along with Blood Oxygenation Level Dependent (BOLD) functional MRI, may play an important role in future research towards the functional organization of the human brain.</description><identifier>ISSN: 0952-3480</identifier><identifier>EISSN: 1099-1492</identifier><identifier>DOI: 10.1002/nbm.1940070113</identifier><identifier>PMID: 8068530</identifier><language>eng</language><publisher>New York: John Wiley & Sons, Ltd</publisher><subject>Angiography - methods ; Hemoglobins - analysis ; Humans ; Image Enhancement - methods ; Magnetic Resonance Imaging - methods ; Motor Cortex - anatomy & histology ; Motor Cortex - blood supply ; Motor Cortex - physiology ; Oxygen - blood ; Visual Cortex - anatomy & histology ; Visual Cortex - blood supply ; Visual Cortex - physiology</subject><ispartof>NMR in biomedicine, 1994-03, Vol.7 (1-2), p.83-88</ispartof><rights>Copyright © 1994 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3783-df08704b86d6345033b0a4d96efe52a06eff63b7df225a75553341a471af02cf3</citedby><cites>FETCH-LOGICAL-c3783-df08704b86d6345033b0a4d96efe52a06eff63b7df225a75553341a471af02cf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fnbm.1940070113$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fnbm.1940070113$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8068530$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Duyn, Jeff H.</creatorcontrib><creatorcontrib>Moonen, Chrit T. W.</creatorcontrib><creatorcontrib>van Yperen, Gert H.</creatorcontrib><creatorcontrib>de Boer, Ruud W.</creatorcontrib><creatorcontrib>Luyten, Peter R.</creatorcontrib><title>Inflow versus deoxyhemoglobin effects in bold functional MRI using gradient echoes at 1.5 T</title><title>NMR in biomedicine</title><addtitle>NMR Biomed</addtitle><description>Modified gradient‐echo MR techniques were applied to study the effects of inflow on functional brain imaging studies using visual and motor cortex stimulation. The results demonstrate that the large signal changes, seen in previously reported gradient‐echo studies at 1.5–2.0 T, are dominated by direct inflow effects, in particular when using a large flip angle and a thin slice. The findings suggest that inflow‐based functional imaging, along with Blood Oxygenation Level Dependent (BOLD) functional MRI, may play an important role in future research towards the functional organization of the human brain.</description><subject>Angiography - methods</subject><subject>Hemoglobins - analysis</subject><subject>Humans</subject><subject>Image Enhancement - methods</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Motor Cortex - anatomy & histology</subject><subject>Motor Cortex - blood supply</subject><subject>Motor Cortex - physiology</subject><subject>Oxygen - blood</subject><subject>Visual Cortex - anatomy & histology</subject><subject>Visual Cortex - blood supply</subject><subject>Visual Cortex - physiology</subject><issn>0952-3480</issn><issn>1099-1492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLxDAUhYMoOj627oSs3HW8eTXtUsXH4AsGRdBFSNubsdo22rTq_HsrMyiuXJ0L95xv8RGyy2DMAPhBk9VjlkoADYyJFTJikKYRkylfJSNIFY-ETGCDbIbwDACJFHydrCcQJ0rAiDxOGlf5D_qObegDLdB_zp-w9rPKZ2VD0TnMu0CHM_NVQV3f5F3pG1vRq-mE9qFsZnTW2qLEpqOYP3kM1HaUjRW93SZrzlYBd5a5Re5OT26Pz6PLm7PJ8eFllAudiKhwkGiQWRIXsZAKhMjAyiKN0aHiFoZ0sch04ThXViulhJDMSs2sA547sUX2F9zX1r_1GDpTlyHHqrIN-j4YHcc6ZUwOxfGimLc-hBadeW3L2rZzw8B82zSDTfNrcxjsLcl9VmPxU1_qG_7p4v9RVjj_h2auj67-sKPFtgwdfv5sbftiYi20MvfXZwaOHuT0YsrNhfgCTYeO_g</recordid><startdate>199403</startdate><enddate>199403</enddate><creator>Duyn, Jeff H.</creator><creator>Moonen, Chrit T. W.</creator><creator>van Yperen, Gert H.</creator><creator>de Boer, Ruud W.</creator><creator>Luyten, Peter R.</creator><general>John Wiley & Sons, Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199403</creationdate><title>Inflow versus deoxyhemoglobin effects in bold functional MRI using gradient echoes at 1.5 T</title><author>Duyn, Jeff H. ; Moonen, Chrit T. W. ; van Yperen, Gert H. ; de Boer, Ruud W. ; Luyten, Peter R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3783-df08704b86d6345033b0a4d96efe52a06eff63b7df225a75553341a471af02cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Angiography - methods</topic><topic>Hemoglobins - analysis</topic><topic>Humans</topic><topic>Image Enhancement - methods</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Motor Cortex - anatomy & histology</topic><topic>Motor Cortex - blood supply</topic><topic>Motor Cortex - physiology</topic><topic>Oxygen - blood</topic><topic>Visual Cortex - anatomy & histology</topic><topic>Visual Cortex - blood supply</topic><topic>Visual Cortex - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Duyn, Jeff H.</creatorcontrib><creatorcontrib>Moonen, Chrit T. W.</creatorcontrib><creatorcontrib>van Yperen, Gert H.</creatorcontrib><creatorcontrib>de Boer, Ruud W.</creatorcontrib><creatorcontrib>Luyten, Peter R.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>NMR in biomedicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Duyn, Jeff H.</au><au>Moonen, Chrit T. W.</au><au>van Yperen, Gert H.</au><au>de Boer, Ruud W.</au><au>Luyten, Peter R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inflow versus deoxyhemoglobin effects in bold functional MRI using gradient echoes at 1.5 T</atitle><jtitle>NMR in biomedicine</jtitle><addtitle>NMR Biomed</addtitle><date>1994-03</date><risdate>1994</risdate><volume>7</volume><issue>1-2</issue><spage>83</spage><epage>88</epage><pages>83-88</pages><issn>0952-3480</issn><eissn>1099-1492</eissn><abstract>Modified gradient‐echo MR techniques were applied to study the effects of inflow on functional brain imaging studies using visual and motor cortex stimulation. The results demonstrate that the large signal changes, seen in previously reported gradient‐echo studies at 1.5–2.0 T, are dominated by direct inflow effects, in particular when using a large flip angle and a thin slice. The findings suggest that inflow‐based functional imaging, along with Blood Oxygenation Level Dependent (BOLD) functional MRI, may play an important role in future research towards the functional organization of the human brain.</abstract><cop>New York</cop><pub>John Wiley & Sons, Ltd</pub><pmid>8068530</pmid><doi>10.1002/nbm.1940070113</doi><tpages>6</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0952-3480 |
ispartof | NMR in biomedicine, 1994-03, Vol.7 (1-2), p.83-88 |
issn | 0952-3480 1099-1492 |
language | eng |
recordid | cdi_proquest_miscellaneous_76679114 |
source | MEDLINE; Wiley Journals |
subjects | Angiography - methods Hemoglobins - analysis Humans Image Enhancement - methods Magnetic Resonance Imaging - methods Motor Cortex - anatomy & histology Motor Cortex - blood supply Motor Cortex - physiology Oxygen - blood Visual Cortex - anatomy & histology Visual Cortex - blood supply Visual Cortex - physiology |
title | Inflow versus deoxyhemoglobin effects in bold functional MRI using gradient echoes at 1.5 T |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T08%3A07%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Inflow%20versus%20deoxyhemoglobin%20effects%20in%20bold%20functional%20MRI%20using%20gradient%20echoes%20at%201.5%20T&rft.jtitle=NMR%20in%20biomedicine&rft.au=Duyn,%20Jeff%20H.&rft.date=1994-03&rft.volume=7&rft.issue=1-2&rft.spage=83&rft.epage=88&rft.pages=83-88&rft.issn=0952-3480&rft.eissn=1099-1492&rft_id=info:doi/10.1002/nbm.1940070113&rft_dat=%3Cproquest_cross%3E76679114%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=76679114&rft_id=info:pmid/8068530&rfr_iscdi=true |