Plasma kinetics and biodistribution of a lipid emulsion resembling low-density lipoprotein in patients with acute leukemia

Low-density lipoprotein (LDL) could be used as a carrier of chemotherapeutic agents to neoplastic cells that overexpress LDL receptors (rLDL), but LDL is difficult to obtain and handle. Recently, it was observed that a protein-free emulsion resembling the lipid portion of LDL (LDE) behave like nativ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1994-09, Vol.54 (17), p.4660-4666
Hauptverfasser:	MARANHAO, R. C, GARICOCHEA, B, SILVA, E. L, DORHLIAC-LLACER, P, CADENA, S. M. S, CELHO, I. J. C, MENEGHETTI, J. C, PILEGGI, F. J. C, CHAMONE, D. A. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Adult Animals Antineoplastic agents Binding, Competitive Biological and medical sciences Chemotherapy Child Drug Carriers - pharmacokinetics Emulsions - pharmacokinetics Female Humans Leukemia, Myeloid - blood Leukemia, Myeloid - diagnostic imaging Leukemia, Myeloid - metabolism Lipoproteins, LDL - pharmacokinetics Lymphocytes - metabolism Male Medical sciences Middle Aged Pharmacology. Drug treatments Precursor Cell Lymphoblastic Leukemia-Lymphoma - blood Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnostic imaging Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism Rabbits Radionuclide Imaging Technetium - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!