Effect of corticosteroids, cyclosporin A, and methotrexate on cytokine release from monocytes and T-cell subsets

Corticosteroids are the most effective drugs in the management of asthma. However, because of their known side effects and the existence of corticosteroid-resistant patients, there is a need for substitute medications in asthma therapy. Using cell lines, in the present study, the two corticosteroids...

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Veröffentlicht in:	Immunopharmacology 1994-05, Vol.27 (3), p.173-179
Hauptverfasser:	Schmidt, Jürgen, Fleiβner, Sandra, Heimann-Weitschat, Irene, Lindstaedt, Roland, Pomberg, Bettina, Werner, Ulrich, Szelenyi, Istvan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - pharmacology Animals Antibodies, Monoclonal Asthma Asthma - drug therapy Asthma - metabolism Beclomethasone - pharmacology Biological and medical sciences CD3 Complex Cell Line Corticosteroid Cyclosporin A Cyclosporine - pharmacology Cytokine Cytokines - metabolism Dexamethasone - pharmacology Dose-Response Relationship, Drug Humans Male Medical sciences Methotrexate Methotrexate - pharmacology Mice Monocytes - drug effects Monocytes - metabolism Pharmacology. Drug treatments Respiratory system T-Lymphocytes - drug effects T-Lymphocytes - metabolism
Online-Zugang:	Volltext
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