Modulating Influence of Barley on the Altered Metabolism of Glucose and of Basement Membranes in the Diabetic Rat
A study was conducted to explore the effects of different sources of dietary carbohydrate on the altered metabolism of basement membrane proteins (type IV collagen and laminin) that occurs in the streptozotocin-diabetic rat. The substitution of barley for sucrose reduced the elevated plasma concentr...
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| Veröffentlicht in: | Annals of nutrition and metabolism 1994, Vol.38 (2), p.61-67 |
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| container_end_page | 67 |
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| container_title | Annals of nutrition and metabolism |
| container_volume | 38 |
| creator | Mahdi, G.S. Naismith, D.J. Price, R.G. Taylor, S.A. Risteli, J. Risteli, L. |
| description | A study was conducted to explore the effects of different sources of dietary carbohydrate on the altered metabolism of basement membrane proteins (type IV collagen and laminin) that occurs in the streptozotocin-diabetic rat. The substitution of barley for sucrose reduced the elevated plasma concentration of 7-S collagen and of laminin P2, peptide fragments that retain antigenicity of the parent proteins. Similar effects were noted in the liver and kidney content of these peptides. It is suggested that the beneficial property of barley is due to its high content of chromium, as has been demonstrated in the study of glucose metabolism. |
| doi_str_mv | 10.1159/000177794 |
| format | Article |
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The substitution of barley for sucrose reduced the elevated plasma concentration of 7-S collagen and of laminin P2, peptide fragments that retain antigenicity of the parent proteins. Similar effects were noted in the liver and kidney content of these peptides. It is suggested that the beneficial property of barley is due to its high content of chromium, as has been demonstrated in the study of glucose metabolism.</description><identifier>ISSN: 0250-6807</identifier><identifier>EISSN: 1421-9697</identifier><identifier>DOI: 10.1159/000177794</identifier><identifier>PMID: 8067686</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger</publisher><subject>Animals ; Basement Membrane - metabolism ; Biological and medical sciences ; Blood Glucose - metabolism ; Chromium ; Collagen - metabolism ; Diabetes Mellitus, Experimental - metabolism ; Diabetes. Impaired glucose tolerance ; Dietary Carbohydrates - administration & dosage ; Dietary Carbohydrates - pharmacology ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Hordeum ; Laminin - metabolism ; Male ; Management. Various non-drug treatments. Langerhans islet grafts ; Medical sciences ; Original Paper ; Rats ; Rats, Sprague-Dawley ; Sucrose - administration & dosage</subject><ispartof>Annals of nutrition and metabolism, 1994, Vol.38 (2), p.61-67</ispartof><rights>1994 S. Karger AG</rights><rights>1994 S. 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The substitution of barley for sucrose reduced the elevated plasma concentration of 7-S collagen and of laminin P2, peptide fragments that retain antigenicity of the parent proteins. Similar effects were noted in the liver and kidney content of these peptides. It is suggested that the beneficial property of barley is due to its high content of chromium, as has been demonstrated in the study of glucose metabolism.</description><subject>Animals</subject><subject>Basement Membrane - metabolism</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - metabolism</subject><subject>Chromium</subject><subject>Collagen - metabolism</subject><subject>Diabetes Mellitus, Experimental - metabolism</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Dietary Carbohydrates - administration & dosage</subject><subject>Dietary Carbohydrates - pharmacology</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Hordeum</subject><subject>Laminin - metabolism</subject><subject>Male</subject><subject>Management. Various non-drug treatments. Langerhans islet grafts</subject><subject>Medical sciences</subject><subject>Original Paper</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Sucrose - administration & dosage</subject><issn>0250-6807</issn><issn>1421-9697</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkM1v1DAUxC1EVZbCgTtIloqQegjY-fDHcSm0VOqChOAcvdjPJcWJt7Zz6H9PVtnuXji9w_zmzWgIecPZR84b_YkxxqWUun5GVrwueaGFls_JipUNK4Ri8gV5mdL9TJWqbk7JqWJCCiVW5GET7OQh9-MdvRmdn3A0SIOjnyF6fKRhpPkP0rXPGNHSDWbogu_TsGOu_WRCQgqjXSwJBxzzTA1dhBET7Rf7lx46zL2hPyG_IicOfMLX-3tGfl99_XX5rbj9cX1zub4tTFWzXLhOc2wsd9zIqnJK1QIqhxJKa2qrQaCzShlRiUprWUrFHTQcQduyFOBMdUY-LH-3MTxMmHI79Mmg93OxMKVWCiF0JcsZvFhAE0NKEV27jf0A8bHlrN3N2x7mndl3-6dTN6A9kPs9Z_39XodkwLt5BdOnA1ZzzrXaRb5dsL8Q7zAeA59Szv8rr79vFqLdWnfscp9yOEJ1w-e6uqn-AYlHoFA</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>Mahdi, G.S.</creator><creator>Naismith, D.J.</creator><creator>Price, R.G.</creator><creator>Taylor, S.A.</creator><creator>Risteli, J.</creator><creator>Risteli, L.</creator><general>S. 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Impaired glucose tolerance</topic><topic>Dietary Carbohydrates - administration & dosage</topic><topic>Dietary Carbohydrates - pharmacology</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Hordeum</topic><topic>Laminin - metabolism</topic><topic>Male</topic><topic>Management. Various non-drug treatments. 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| fulltext | fulltext |
| identifier | ISSN: 0250-6807 |
| ispartof | Annals of nutrition and metabolism, 1994, Vol.38 (2), p.61-67 |
| issn | 0250-6807 1421-9697 |
| language | eng |
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| source | MEDLINE; JSTOR Archive Collection A-Z Listing |
| subjects | Animals Basement Membrane - metabolism Biological and medical sciences Blood Glucose - metabolism Chromium Collagen - metabolism Diabetes Mellitus, Experimental - metabolism Diabetes. Impaired glucose tolerance Dietary Carbohydrates - administration & dosage Dietary Carbohydrates - pharmacology Endocrine pancreas. Apud cells (diseases) Endocrinopathies Hordeum Laminin - metabolism Male Management. Various non-drug treatments. Langerhans islet grafts Medical sciences Original Paper Rats Rats, Sprague-Dawley Sucrose - administration & dosage |
| title | Modulating Influence of Barley on the Altered Metabolism of Glucose and of Basement Membranes in the Diabetic Rat |
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