Mechanism of the abnormal vitamin k‐dependent γ‐carboxylation process in human hepatocellular carcinomas

Background. An important marker for hepatocellular carcinoma is the presence of des‐γ‐carboxy (abnormal) prothrombin. However, the molecular basis for the reduced carboxylation of prothrombin is unknown. Methods. Two groups of patients were defined according to the absence (Group I, n = 7) or presen...

Ausführliche Beschreibung