Characterization of Human Serum-Resistant and Serum-Sensitive Clones from a Single Trypanosoma brucei gambiense Parental Clone

A protocol was developed to select clones of Trypanosoma brucei gambiense having different levels of resistance to normal human serum. Human serum-resistant clones were selected from a single parental clone by continuous serum treatment of infected immunosuppressed mice. Human serum-sensitive revert...

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Veröffentlicht in:	The Journal of parasitology 1994-08, Vol.80 (4), p.550-557
Hauptverfasser:	Ortiz, Juan Carlos, Sechelski, John B., Seed, John R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Antiserum Biochemistry Biological and medical sciences Blood - immunology Blotting, Western Electrophoresis Electrophoresis, Polyacrylamide Gel Experimental protozoal diseases and models Gels Humans Immune Sera - immunology Immunology Immunosuppression Infectious diseases Medical sciences Mice Mice, Inbred C3H Mice, Inbred Strains Parasitemia Parasitic diseases Parasitology Phenotype Protozoal diseases Tropical medicine Trypanosoma brucei gambiense - genetics Trypanosoma brucei gambiense - immunology Trypanosome Trypanosomiasis, African - blood Trypanosomiasis, African - immunology Variant Surface Glycoproteins, Trypanosoma - immunology
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