Polymorphous high grade B cell lymphoma is the predominant type of spontaneous primary cerebral malignant lymphomas. Histological and immunomorphological evaluation of computed tomography-guided stereotactic brain biopsies
In this retrospective study, a series of 54 patients (1982-1989) with sporadic primary cerebral malignant lymphomas is presented. All diagnoses were uniformly done on computed tomography-guided stereotactic brain biopsies according to histological criteria and immunomorphological data. In this serie...
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Veröffentlicht in: | The American journal of surgical pathology 1994-09, Vol.18 (9), p.931-937 |
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creator | SCHWECHHEIMER, K BRAUS, D. F SCHWARZKOPF, G FELLER, A. C VOLK, B MÜLLER-HERMELINK, H. K |
description | In this retrospective study, a series of 54 patients (1982-1989) with sporadic primary cerebral malignant lymphomas is presented. All diagnoses were uniformly done on computed tomography-guided stereotactic brain biopsies according to histological criteria and immunomorphological data. In this series, the tumors were predominantly (25 of 48; 52%) classified as polymorphous high-grade blastic B cell lymphomas. This lymphoma type is therefore regarded as the most common type of sporadic primary cerebral non-Hodgkin's lymphoma. Severe regression (++/ ), which may dramatically alter the morphological appearance of a brain lymphoma, was found in 24 of 28 (86%) of cases with glucocorticoid administration prior to stereotactic brain biopsy. |
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Severe regression (++/ ), which may dramatically alter the morphological appearance of a brain lymphoma, was found in 24 of 28 (86%) of cases with glucocorticoid administration prior to stereotactic brain biopsy.</description><identifier>ISSN: 0147-5185</identifier><identifier>EISSN: 1532-0979</identifier><identifier>DOI: 10.1097/00000478-199409000-00008</identifier><identifier>PMID: 8067514</identifier><identifier>CODEN: AJSPDX</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adolescent ; Adult ; Aged ; Biological and medical sciences ; Biopsy - instrumentation ; Biopsy - methods ; Brain Neoplasms - chemistry ; Brain Neoplasms - pathology ; Female ; Hematologic and hematopoietic diseases ; Humans ; Immunoenzyme Techniques ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Lymphoma, B-Cell - chemistry ; Lymphoma, B-Cell - pathology ; Lymphoma, Non-Hodgkin - chemistry ; Lymphoma, Non-Hodgkin - pathology ; Male ; Medical sciences ; Middle Aged ; Retrospective Studies ; Stereotaxic Techniques ; Tomography, X-Ray Computed</subject><ispartof>The American journal of surgical pathology, 1994-09, Vol.18 (9), p.931-937</ispartof><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c254t-dc30c19f0f7c22c648699c6404834007854c9f68685e68df19da50220adfd1823</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3410292$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8067514$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SCHWECHHEIMER, K</creatorcontrib><creatorcontrib>BRAUS, D. F</creatorcontrib><creatorcontrib>SCHWARZKOPF, G</creatorcontrib><creatorcontrib>FELLER, A. C</creatorcontrib><creatorcontrib>VOLK, B</creatorcontrib><creatorcontrib>MÜLLER-HERMELINK, H. K</creatorcontrib><title>Polymorphous high grade B cell lymphoma is the predominant type of spontaneous primary cerebral malignant lymphomas. Histological and immunomorphological evaluation of computed tomography-guided stereotactic brain biopsies</title><title>The American journal of surgical pathology</title><addtitle>Am J Surg Pathol</addtitle><description>In this retrospective study, a series of 54 patients (1982-1989) with sporadic primary cerebral malignant lymphomas is presented. All diagnoses were uniformly done on computed tomography-guided stereotactic brain biopsies according to histological criteria and immunomorphological data. In this series, the tumors were predominantly (25 of 48; 52%) classified as polymorphous high-grade blastic B cell lymphomas. This lymphoma type is therefore regarded as the most common type of sporadic primary cerebral non-Hodgkin's lymphoma. Severe regression (++/ ), which may dramatically alter the morphological appearance of a brain lymphoma, was found in 24 of 28 (86%) of cases with glucocorticoid administration prior to stereotactic brain biopsy.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Biopsy - instrumentation</subject><subject>Biopsy - methods</subject><subject>Brain Neoplasms - chemistry</subject><subject>Brain Neoplasms - pathology</subject><subject>Female</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Immunoenzyme Techniques</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lymphoma, B-Cell - chemistry</subject><subject>Lymphoma, B-Cell - pathology</subject><subject>Lymphoma, Non-Hodgkin - chemistry</subject><subject>Lymphoma, Non-Hodgkin - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Stereotaxic Techniques</subject><subject>Tomography, X-Ray Computed</subject><issn>0147-5185</issn><issn>1532-0979</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9UcmO1DAUtBBoaAY-AckHxC2D7TiJfYQRMEgjwQHOkdtLYhQv2A5S_yzfgjOdbl-eXFVvURUAEKM7jPjwAW2PDqzBnFPE66fZEPYMHHDXkqZq-HNwQJgOTYdZ9xK8yvk3QpgwTG7ADUP90GF6AP9-hOXkQopzWDOc7TTDKQml4Sco9bLASlbKCWgzLLOGMWkVnPXCF1hOUcNgYI7BF-H1NiEm60Q61eakj0ks0InFTk_yy6h8Bx9sLmEJk5VVIbyC1rnVh_MdF1z_Fcsqig1-WyKDi2vRCpYqqyfG-dRMq1UVyaUuC0XIYiWsS62HRxtitjq_Bi-MWLJ-s9db8OvL55_3D83j96_f7j8-NpJ0tDRKtkhibpAZJCGyp6znvBZEWUsRGlhHJTc961mne6YM5kp0iBAklFGYkfYWvD_PjSn8WXUuo7N5M_Bsyzj09ZEBVyE7C2UKOSdtxt2xEaNxi3a8RDteo32CWG19u-9Yj06ra-OeZeXf7bzI1T-ThJc2X2UtxYhw0v4HM3ey7w</recordid><startdate>199409</startdate><enddate>199409</enddate><creator>SCHWECHHEIMER, K</creator><creator>BRAUS, D. 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Myelofibrosis</topic><topic>Lymphoma, B-Cell - chemistry</topic><topic>Lymphoma, B-Cell - pathology</topic><topic>Lymphoma, Non-Hodgkin - chemistry</topic><topic>Lymphoma, Non-Hodgkin - pathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Stereotaxic Techniques</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SCHWECHHEIMER, K</creatorcontrib><creatorcontrib>BRAUS, D. F</creatorcontrib><creatorcontrib>SCHWARZKOPF, G</creatorcontrib><creatorcontrib>FELLER, A. C</creatorcontrib><creatorcontrib>VOLK, B</creatorcontrib><creatorcontrib>MÜLLER-HERMELINK, H. 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Histological and immunomorphological evaluation of computed tomography-guided stereotactic brain biopsies</atitle><jtitle>The American journal of surgical pathology</jtitle><addtitle>Am J Surg Pathol</addtitle><date>1994-09</date><risdate>1994</risdate><volume>18</volume><issue>9</issue><spage>931</spage><epage>937</epage><pages>931-937</pages><issn>0147-5185</issn><eissn>1532-0979</eissn><coden>AJSPDX</coden><abstract>In this retrospective study, a series of 54 patients (1982-1989) with sporadic primary cerebral malignant lymphomas is presented. All diagnoses were uniformly done on computed tomography-guided stereotactic brain biopsies according to histological criteria and immunomorphological data. In this series, the tumors were predominantly (25 of 48; 52%) classified as polymorphous high-grade blastic B cell lymphomas. This lymphoma type is therefore regarded as the most common type of sporadic primary cerebral non-Hodgkin's lymphoma. Severe regression (++/ ), which may dramatically alter the morphological appearance of a brain lymphoma, was found in 24 of 28 (86%) of cases with glucocorticoid administration prior to stereotactic brain biopsy.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>8067514</pmid><doi>10.1097/00000478-199409000-00008</doi><tpages>7</tpages></addata></record> |
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subjects | Adolescent Adult Aged Biological and medical sciences Biopsy - instrumentation Biopsy - methods Brain Neoplasms - chemistry Brain Neoplasms - pathology Female Hematologic and hematopoietic diseases Humans Immunoenzyme Techniques Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, B-Cell - chemistry Lymphoma, B-Cell - pathology Lymphoma, Non-Hodgkin - chemistry Lymphoma, Non-Hodgkin - pathology Male Medical sciences Middle Aged Retrospective Studies Stereotaxic Techniques Tomography, X-Ray Computed |
title | Polymorphous high grade B cell lymphoma is the predominant type of spontaneous primary cerebral malignant lymphomas. Histological and immunomorphological evaluation of computed tomography-guided stereotactic brain biopsies |
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