Myasthenia gravis complicating Charcot-Marie-Tooth disease: report of a case

Generalized myasthenia gravis developed in a 61 year old man with the hypertrophic form of Charcot-Marie-Tooth disease (CMT). While ocular abnormalities mimicking myasthenia gravis have been reported in CMT, and two patients with atypical CMT have had features consistent with ocular myasthenia, this...

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Veröffentlicht in:	Journal of clinical neuro-ophthalmology 1985-06, Vol.5 (2), p.76-80
Hauptverfasser:	BERGER, J. R, RAM AYYAR, D, KIMURA, I, KOVACS, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Blepharoptosis - drug therapy Blepharoptosis - etiology Charcot-Marie-Tooth Disease - complications Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Humans Male Medical sciences Middle Aged Muscular Atrophy - complications Myasthenia Gravis - etiology Neurology Ophthalmoplegia - etiology
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Zusammenfassung:	Generalized myasthenia gravis developed in a 61 year old man with the hypertrophic form of Charcot-Marie-Tooth disease (CMT). While ocular abnormalities mimicking myasthenia gravis have been reported in CMT, and two patients with atypical CMT have had features consistent with ocular myasthenia, this is the first report of generalized myasthenia gravis complicating CMT. The estimated prevalence for the concurrence of these two disorders suggests that it is an extremely rare event.
ISSN:	0272-846X