Evidence that lithium induces a glutamatergic : nitric oxide-mediated response in rat brain

Studies have indicated the involvement of a glutamatergic mechanism in lithium (Li+) action. Glutamatergic agonists, such as kainic acid, are known to promote the synthesis of nitric oxide (NO) and to increase cGMP, while Li+ has displayed a similar, yet unexplained, ability to increase cGMP. NO syn...

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Veröffentlicht in:	Neurochemical research 1994-04, Vol.19 (4), p.469-474
Hauptverfasser:	HARVEY, B. M, CARSTENS, M. E, TALJAARD, J. J. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine - analogs & derivatives Arginine - pharmacology Biological and medical sciences Cerebral Cortex - drug effects Cerebral Cortex - metabolism Cyclic GMP - metabolism Drinking Behavior - drug effects Glutamates - pharmacology Kainic Acid - pharmacology Lithium Chloride - pharmacology Male Medical sciences Neuropharmacology NG-Nitroarginine Methyl Ester Nitric Oxide - biosynthesis Nitric Oxide - physiology Pharmacology. Drug treatments Polyuria Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Rats Rats, Wistar Stereotyped Behavior - drug effects
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