A CD and an nmr study of multiple bradykinin conformations in aqueous trifluoroethanol solutions

CD and nmr studies have been carried out on aqueous trifluoroethanol (TFE) solutions of bradykinin (BK) and a bradykinin antagonist. The CD results exhibit a striking effect of TFE on the spectra of BK, with sequence Arg‐Pro‐Pro‐Gly‐Phe‐Ser‐Pro‐Phe‐Arg, and the BK antagonist, with sequence D‐Arg‐Arg...

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Veröffentlicht in:	Biopolymers 1994-07, Vol.34 (7), p.869-878
Hauptverfasser:	Cann, John R., Liu, Xiaohong, Stewart, John M., Gera, Lajos, Kotovych, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bradykinin - chemistry Circular Dichroism Magnetic Resonance Spectroscopy Molecular Sequence Data Protein Conformation Solutions Trifluoroethanol Water
Online-Zugang:	Volltext
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