Simple tandem repeat DNA polymorphism in the human glycogen synthase gene is associated with NIDDM in Japanese subjects

We investigated the possible association between alleles of a simple tandem repeat DNA polymorphism in the human glycogen synthase gene and non-obese non-insulin-dependent diabetes (NIDDM) in Japanese subjects. Nine alleles (-4G, -3G, -2G, -1G, 0G, 1G, 2G, 3G, and 4G) were identified in the study gr...

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Veröffentlicht in:	Diabetologia 1994-05, Vol.37 (5), p.536-539
Hauptverfasser:	KUROYAMA, H, SANKE, T, OHAGI, S, FURUTA, M, FURUTA, H, NANJO, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age of Onset Alleles Base Sequence Biological and medical sciences Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - enzymology Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance DNA - blood DNA - genetics DNA - isolation & purification DNA Primers Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Genetic Markers Glycogen Synthase - genetics Humans Japan Leukocytes - metabolism Medical sciences Molecular Sequence Data Polymerase Chain Reaction - methods Polymorphism, Genetic Reference Values Repetitive Sequences, Nucleic Acid
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