Maffucci's syndrome associated with intracranial chordoma: case report

This report discusses Maffucci's syndrome associated with intracranial chordoma. Of the 170 reported cases of this syndrome, only 27 have been associated with intracranial lesions and none was involved with intracranial chordoma. Chordomas are occasionally difficult to differentiate from chondr...

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Veröffentlicht in:	Neurosurgery 1994-05, Vol.34 (5), p.907-909
Hauptverfasser:	Nakayama, Y, Takeno, Y, Tsugu, H, Tomonaga, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - analysis Brain Neoplasms - diagnosis Brain Neoplasms - genetics Brain Neoplasms - pathology Brain Neoplasms - surgery Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - pathology Chordoma - diagnosis Chordoma - genetics Chordoma - pathology Chordoma - surgery Chromosomes, Human, Pair 1 Enchondromatosis - diagnosis Enchondromatosis - genetics Enchondromatosis - pathology Enchondromatosis - surgery Humans Male Medulla Oblongata - pathology Medulla Oblongata - surgery Middle Aged Pons - pathology Pons - surgery
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Beschreibung
Zusammenfassung:	This report discusses Maffucci's syndrome associated with intracranial chordoma. Of the 170 reported cases of this syndrome, only 27 have been associated with intracranial lesions and none was involved with intracranial chordoma. Chordomas are occasionally difficult to differentiate from chondroma and chondrosarcoma. An immunohistochemical analysis was able to prove, however, that the chordoma of this case significantly differed from chondroma and chondrosarcoma.
ISSN:	0148-396X
DOI:	10.1227/00006123-199405000-00019