High-resolution mass spectrometer for protein chemistry

High-resolution mass spectrometer for protein chemistry

Matrix-assisted laser desorption/ionization is an accurate and sensitive method for measuring the molecular weights of peptides and proteins. Usually time-of-flight mass spectrometry is used to detect the laser-produced ions, but a new method called Fourier transform mass spectrometry offers greater...

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Veröffentlicht in:Nature (London) 1994-08, Vol.370 (6488), p.393-395
Hauptverfasser: Li, Yunzhi, Hunter, Richard L., Mclver, Robert T.
Format: Artikel
Sprache:eng
Schlagworte:
Analytical, structural and metabolic biochemistry
Animals
Biological and medical sciences
Cattle
Chemistry
Fourier Analysis
Fourier transforms
Fundamental and applied biological sciences. Psychology
General aspects, investigation methods
Humanities and Social Sciences
Instruments
Insulin - chemistry
Lasers
Mass spectrometry
Mass Spectrometry - instrumentation
Mass Spectrometry - methods
multidisciplinary
product-review
Proteins
Proteins - chemistry
Science
Science (multidisciplinary)
Scientific imaging
Vasopressins - chemistry
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Beschreibung
Zusammenfassung:Matrix-assisted laser desorption/ionization is an accurate and sensitive method for measuring the molecular weights of peptides and proteins. Usually time-of-flight mass spectrometry is used to detect the laser-produced ions, but a new method called Fourier transform mass spectrometry offers greater sensitivity and much higher mass measurement accuracy.
ISSN:0028-0836
1476-4687
DOI:10.1038/370393a0