Fine Specificity of T Cell Lines and Clones That Are Capable of Inducing Autoimmune Manifestations in Mice

Myasthenia gravis is a T-cell-regulated, antibody-mediated autoimmune disease. The synthetic peptides p195-212 and p259-271, which represent sequences of the human acetylcholine receptor α-subunit, preferentially stimulated T cells of patients with myasthenia gravis and were found to be immunodomina...

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