The hypothalamo-pituitary-gonadal axis in uremic patients receiving hemodialysis in childhood
Eight uremic patients (aged 16-21) reseiving hemodialysis in childhood, were studied on the hypothelamo-pituitary gonadal axis.1. The gonadal dysfunction was implicated by the findings of low serum testosterone, high luteinizing hormone (LH) levels, hyporesponsiveness in human chorionic gonadotropin...
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| Veröffentlicht in: | Nihon Jinzo Gakkai shi 1985, Vol.27(10), pp.1445-1449 |
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| container_issue | 10 |
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| container_title | Nihon Jinzo Gakkai shi |
| container_volume | 27 |
| creator | FUJISAWA, TAKUJI KINOSHITA, SHOHEI TANAKA, EIICHIROU OOBU, KEIZOU ITO, YUHEI YOSHIMOTO, MASANAGA SHINDO, SHIZUO YAMASHITA, FUMIO |
| description | Eight uremic patients (aged 16-21) reseiving hemodialysis in childhood, were studied on the hypothelamo-pituitary gonadal axis.1. The gonadal dysfunction was implicated by the findings of low serum testosterone, high luteinizing hormone (LH) levels, hyporesponsiveness in human chorionic gonadotropin (HCG) test.2. Delayed and prolonged response in LH-RH test suggested the decrease in metabolic clearance rate (MCR) of LH.3. The findings of two cases whose testosterone levels were low and LH levels were high, suggested the hypothalamic dysfunction.4. Pituitary function was normal.5. The mean value of serum LH in the female was higher that that in the male patients. The underlying mechanism is unknown.6. All patients had the clinical evidence of puberty in spite of the hormonal dysfunction in the hypothalamo'pituitary-gonadal axis. |
| doi_str_mv | 10.14842/jpnjnephrol1959.27.1445 |
| format | Article |
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The gonadal dysfunction was implicated by the findings of low serum testosterone, high luteinizing hormone (LH) levels, hyporesponsiveness in human chorionic gonadotropin (HCG) test.2. Delayed and prolonged response in LH-RH test suggested the decrease in metabolic clearance rate (MCR) of LH.3. The findings of two cases whose testosterone levels were low and LH levels were high, suggested the hypothalamic dysfunction.4. Pituitary function was normal.5. The mean value of serum LH in the female was higher that that in the male patients. The underlying mechanism is unknown.6. All patients had the clinical evidence of puberty in spite of the hormonal dysfunction in the hypothalamo'pituitary-gonadal axis.</description><identifier>ISSN: 0385-2385</identifier><identifier>EISSN: 1884-0728</identifier><identifier>DOI: 10.14842/jpnjnephrol1959.27.1445</identifier><identifier>PMID: 4094168</identifier><language>jpn</language><publisher>Japan: Japanese Society of Nephrology</publisher><subject>Adolescent ; Adult ; Children ; Chronic reral failure ; Female ; Gonads - physiopathology ; Humans ; Hypothalamo-Hypophyseal System - physiopathology ; hypothalamo-pituiatry-gonadal axis ; Kidney Failure, Chronic - physiopathology ; Luteinizing Hormone - blood ; Male ; Renal Dialysis ; Testosterone - blood ; Time Factors ; Uremia - physiopathology</subject><ispartof>The Japanese Journal of Nephrology, 1985, Vol.27(10), pp.1445-1449</ispartof><rights>Japanese Society of Nephrology</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1876,4009,27902,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4094168$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>FUJISAWA, TAKUJI</creatorcontrib><creatorcontrib>KINOSHITA, SHOHEI</creatorcontrib><creatorcontrib>TANAKA, EIICHIROU</creatorcontrib><creatorcontrib>OOBU, KEIZOU</creatorcontrib><creatorcontrib>ITO, YUHEI</creatorcontrib><creatorcontrib>YOSHIMOTO, MASANAGA</creatorcontrib><creatorcontrib>SHINDO, SHIZUO</creatorcontrib><creatorcontrib>YAMASHITA, FUMIO</creatorcontrib><title>The hypothalamo-pituitary-gonadal axis in uremic patients receiving hemodialysis in childhood</title><title>Nihon Jinzo Gakkai shi</title><addtitle>Jpn J Nephrol</addtitle><description>Eight uremic patients (aged 16-21) reseiving hemodialysis in childhood, were studied on the hypothelamo-pituitary gonadal axis.1. The gonadal dysfunction was implicated by the findings of low serum testosterone, high luteinizing hormone (LH) levels, hyporesponsiveness in human chorionic gonadotropin (HCG) test.2. Delayed and prolonged response in LH-RH test suggested the decrease in metabolic clearance rate (MCR) of LH.3. The findings of two cases whose testosterone levels were low and LH levels were high, suggested the hypothalamic dysfunction.4. Pituitary function was normal.5. The mean value of serum LH in the female was higher that that in the male patients. The underlying mechanism is unknown.6. All patients had the clinical evidence of puberty in spite of the hormonal dysfunction in the hypothalamo'pituitary-gonadal axis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Children</subject><subject>Chronic reral failure</subject><subject>Female</subject><subject>Gonads - physiopathology</subject><subject>Humans</subject><subject>Hypothalamo-Hypophyseal System - physiopathology</subject><subject>hypothalamo-pituiatry-gonadal axis</subject><subject>Kidney Failure, Chronic - physiopathology</subject><subject>Luteinizing Hormone - blood</subject><subject>Male</subject><subject>Renal Dialysis</subject><subject>Testosterone - blood</subject><subject>Time Factors</subject><subject>Uremia - physiopathology</subject><issn>0385-2385</issn><issn>1884-0728</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkT9PwzAUxC0EKlXpR0DKxJZix05sj6jin1TBUkYUOclL48iJg-0g-u0JatSB5W74nU569xCKCN4QJlhy3w5928PQOGuITOUm4RNg6QVaEiFYjHkiLtESU5HGySTXaO29LjARHNOUswVaMCwZycQSfe4biJrjYEOjjOpsPOgw6qDcMT7YXlXKROpH-0j30eig02U0qKChDz5yUIL-1v0haqCzlVbm6E_JstGmaqytbtBVrYyH9ewr9PH0uN--xLv359ftwy5uEyZDDLUoBAXFiJCUKpAlz1JeiayoGKUZYSBkgVOV1QWfvARZkILVJE0EwTUndIXuTr2Ds18j-JB32pdgjOrBjj6f6qSUlE_B2zk4Fh1U-eB0N92az3tM_O3EWx_UAc5cuaBLA_m_5fOE5wTP-veCc7BslMuhp79DD4Rs</recordid><startdate>1985</startdate><enddate>1985</enddate><creator>FUJISAWA, TAKUJI</creator><creator>KINOSHITA, SHOHEI</creator><creator>TANAKA, EIICHIROU</creator><creator>OOBU, KEIZOU</creator><creator>ITO, YUHEI</creator><creator>YOSHIMOTO, MASANAGA</creator><creator>SHINDO, SHIZUO</creator><creator>YAMASHITA, FUMIO</creator><general>Japanese Society of Nephrology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>1985</creationdate><title>The hypothalamo-pituitary-gonadal axis in uremic patients receiving hemodialysis in childhood</title><author>FUJISAWA, TAKUJI ; KINOSHITA, SHOHEI ; TANAKA, EIICHIROU ; OOBU, KEIZOU ; ITO, YUHEI ; YOSHIMOTO, MASANAGA ; SHINDO, SHIZUO ; YAMASHITA, FUMIO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j249t-ef8b83ea418933ae9c7657d86bd433614e89b05a6fb7b05ce9b1b4f152810f713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>jpn</language><creationdate>1985</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Children</topic><topic>Chronic reral failure</topic><topic>Female</topic><topic>Gonads - physiopathology</topic><topic>Humans</topic><topic>Hypothalamo-Hypophyseal System - physiopathology</topic><topic>hypothalamo-pituiatry-gonadal axis</topic><topic>Kidney Failure, Chronic - physiopathology</topic><topic>Luteinizing Hormone - blood</topic><topic>Male</topic><topic>Renal Dialysis</topic><topic>Testosterone - blood</topic><topic>Time Factors</topic><topic>Uremia - physiopathology</topic><toplevel>online_resources</toplevel><creatorcontrib>FUJISAWA, TAKUJI</creatorcontrib><creatorcontrib>KINOSHITA, SHOHEI</creatorcontrib><creatorcontrib>TANAKA, EIICHIROU</creatorcontrib><creatorcontrib>OOBU, KEIZOU</creatorcontrib><creatorcontrib>ITO, YUHEI</creatorcontrib><creatorcontrib>YOSHIMOTO, MASANAGA</creatorcontrib><creatorcontrib>SHINDO, SHIZUO</creatorcontrib><creatorcontrib>YAMASHITA, FUMIO</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Nihon Jinzo Gakkai shi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FUJISAWA, TAKUJI</au><au>KINOSHITA, SHOHEI</au><au>TANAKA, EIICHIROU</au><au>OOBU, KEIZOU</au><au>ITO, YUHEI</au><au>YOSHIMOTO, MASANAGA</au><au>SHINDO, SHIZUO</au><au>YAMASHITA, FUMIO</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The hypothalamo-pituitary-gonadal axis in uremic patients receiving hemodialysis in childhood</atitle><jtitle>Nihon Jinzo Gakkai shi</jtitle><addtitle>Jpn J Nephrol</addtitle><date>1985</date><risdate>1985</risdate><volume>27</volume><issue>10</issue><spage>1445</spage><epage>1449</epage><pages>1445-1449</pages><issn>0385-2385</issn><eissn>1884-0728</eissn><abstract>Eight uremic patients (aged 16-21) reseiving hemodialysis in childhood, were studied on the hypothelamo-pituitary gonadal axis.1. 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| fulltext | fulltext |
| identifier | ISSN: 0385-2385 |
| ispartof | The Japanese Journal of Nephrology, 1985, Vol.27(10), pp.1445-1449 |
| issn | 0385-2385 1884-0728 |
| language | jpn |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese |
| subjects | Adolescent Adult Children Chronic reral failure Female Gonads - physiopathology Humans Hypothalamo-Hypophyseal System - physiopathology hypothalamo-pituiatry-gonadal axis Kidney Failure, Chronic - physiopathology Luteinizing Hormone - blood Male Renal Dialysis Testosterone - blood Time Factors Uremia - physiopathology |
| title | The hypothalamo-pituitary-gonadal axis in uremic patients receiving hemodialysis in childhood |
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