Effects of hormones (calcitonin, GIP) and pharmacological antagonists (ranitidine and famotidine) on isolated rat parietal cells

The rationale for the present study was to compare calcitonin and gastric inhibitory polypeptide (GIP) versus two histamine H 2 receptor antagonists with respect to their potency of inhibiting parietal cell functions. Adenylate cyclase activity and acid production ([ 14C]aminopyrine uptake) of isola...

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Veröffentlicht in:	Regulatory peptides 1985-11, Vol.12 (4), p.297-308
Hauptverfasser:	Schepp, W., Miederer, S.E., Ruoff, H.-J.
Format:	Artikel
Sprache:	eng
Schlagworte:	[ 14C]aminopyrine uptake adenylate cyclase activity Adenylyl Cyclases - metabolism Aminopyrine - metabolism Animals Biological and medical sciences calcitonin Calcitonin - pharmacology Cell Separation Dose-Response Relationship, Drug Famotidine Fundamental and applied biological sciences. Psychology gastric inhibitory polypeptide Gastric Inhibitory Polypeptide - pharmacology histamine H 2 receptor antagonists isolated parietal cells (rat) Parietal Cells, Gastric - drug effects Ranitidine - pharmacology Rats Stomach Thiazoles - pharmacology Vertebrates: digestive system
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