Increased Extracellular Serotonin in Rat Brain After Systemic or Intraraphe Administration of Morphine

: The effect of morphine on serotonin (5‐HT) and 5‐hydroxyindoleacetic acid (5‐HIAA) in the CNS of unanesthetized rats was investigated by microdialysis. Morphine was administered either subcutaneously, by local perfusion into the diencephalon, or by intraraphe microinjection. Systemic administratio...

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Veröffentlicht in:	Journal of neurochemistry 1994-08, Vol.63 (2), p.517-524
Hauptverfasser:	Tao, Rui, Auerbach, Sidney B.
Format:	Artikel
Sprache:	eng
Schlagworte:	5‐Hydroxyindoleacetic acid Analgesics Animals Biological and medical sciences Brain - drug effects Brain - metabolism CNS Corpus Striatum - drug effects Corpus Striatum - physiology Dialysis Diencephalon - drug effects Diencephalon - physiology Extracellular Space - metabolism Hippocampus - drug effects Hippocampus - physiology Hydroxyindoleacetic Acid - metabolism Infusions, Parenteral Injections, Subcutaneous Male Medical sciences Microinjections Morphine Morphine - administration & dosage Morphine - pharmacology Neuropharmacology Pharmacology. Drug treatments Raphe Nuclei - drug effects Raphe Nuclei - physiology Rat Rats Rats, Sprague-Dawley Serotonin Serotonin - metabolism Stereotaxic Techniques Time Factors
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