Evidence that homologous ssDNA is present in scrapie, Creutzfeldt-Jakob disease, and bovine spongiform encephalopathy

Homogenized brain tissue from scrapie-infected hamsters and uninfected hamsters was subjected to sub-cellular fractionation to isolate nemavirus. Nucleic acid was extracted from these fractions, which also contained mitochondria. Agarose-gel electrophoresis revealed a band corresponding to the size...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 1994, Vol.724 (1), p.314-326
1. Verfasser:	Narang, H.K
Format:	Artikel
Sprache:	eng
Schlagworte:	ACIDE NUCLEIQUE ACIDOS NUCLEICOS ADN ANIMAL VIRUSES Animals Base Sequence BRAIN Cattle CEREBRO Creutzfeldt-Jakob Syndrome - genetics Cricetinae DNA DNA HYBRIDIZATION DNA PROBES DNA, Single-Stranded - isolation & purification Electrophoresis, Agar Gel ENCEFALOPATIA ESPONGIFORME ENCEPHALE ENCEPHALOPATHIE SPONGIFORME Encephalopathy, Bovine Spongiform - genetics HIBRIDACION DE ADN Humans HYBRIDATION D'ADN MITOCHONDRIA MITOCHONDRIE MITOCONDRIA Molecular Sequence Data NEMAVIRUS NERVOUS SYSTEM DISEASES NUCLEIC ACIDS Scrapie - genetics SCRAPIE AGENT SPONGIFORM ENCEPHALOPATHY TRASTORNOS DEL SISTEMA NERVIOSO TROUBLE DU SYSTEME NERVEUX VIROSE VIROSES VIROSIS VIRUS DE LOS ANIMALES VIRUS DES ANIMAUX VIRUS TEMBLADERA DE LOS OVINOS VIRUS TREMBLANTE DU MOUTON
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