Primary mucinous carcinoma of the skin with metastases to the lymph nodes
Primary mucinous carcinoma is a rare sweat-gland neoplasm of the skin with a tendency to grow slowly. Although the neoplasm persists locally in nearly half of the cases after attempts at removal, metastases to regional lymph nodes and widespread metastases are uncommon. We present a case of primary...
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| Veröffentlicht in: | The American journal of dermatopathology 1985-10, Vol.7 (5), p.461-469 |
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| container_end_page | 469 |
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| container_issue | 5 |
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| container_title | The American journal of dermatopathology |
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| creator | PILGRIM, J. P KLOSS, S. G WOLFISH, P. S HENG, M. C. Y |
| description | Primary mucinous carcinoma is a rare sweat-gland neoplasm of the skin with a tendency to grow slowly. Although the neoplasm persists locally in nearly half of the cases after attempts at removal, metastases to regional lymph nodes and widespread metastases are uncommon. We present a case of primary mucinous carcinoma in an axilla with metastases to the axillary lymph nodes and propose a hypothesis explaining the slow rate of growth, based on our findings of a paucity of both blood vessels and macrophages in the neoplasm. Electron microscopy revealed mucin production by the dark cell and its extracellular secretion, which supports the theory of eccrine differentiation of the neoplasm. |
| doi_str_mv | 10.1097/00000372-198510000-00011 |
| format | Article |
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Electron microscopy revealed mucin production by the dark cell and its extracellular secretion, which supports the theory of eccrine differentiation of the neoplasm.</description><identifier>ISSN: 0193-1091</identifier><identifier>EISSN: 1533-0311</identifier><identifier>DOI: 10.1097/00000372-198510000-00011</identifier><identifier>PMID: 3004247</identifier><identifier>CODEN: AJODDB</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adenocarcinoma, Mucinous - pathology ; Adenocarcinoma, Mucinous - ultrastructure ; Aged ; Biological and medical sciences ; Dermatology ; Humans ; Lymph Nodes - pathology ; Lymph Nodes - ultrastructure ; Lymphatic Metastasis ; Male ; Medical sciences ; Microscopy, Electron ; Skin Neoplasms - pathology ; Skin Neoplasms - ultrastructure ; Tumors of the skin and soft tissue. 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S</creatorcontrib><creatorcontrib>HENG, M. C. Y</creatorcontrib><title>Primary mucinous carcinoma of the skin with metastases to the lymph nodes</title><title>The American journal of dermatopathology</title><addtitle>Am J Dermatopathol</addtitle><description>Primary mucinous carcinoma is a rare sweat-gland neoplasm of the skin with a tendency to grow slowly. Although the neoplasm persists locally in nearly half of the cases after attempts at removal, metastases to regional lymph nodes and widespread metastases are uncommon. We present a case of primary mucinous carcinoma in an axilla with metastases to the axillary lymph nodes and propose a hypothesis explaining the slow rate of growth, based on our findings of a paucity of both blood vessels and macrophages in the neoplasm. Electron microscopy revealed mucin production by the dark cell and its extracellular secretion, which supports the theory of eccrine differentiation of the neoplasm.</description><subject>Adenocarcinoma, Mucinous - pathology</subject><subject>Adenocarcinoma, Mucinous - ultrastructure</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Humans</subject><subject>Lymph Nodes - pathology</subject><subject>Lymph Nodes - ultrastructure</subject><subject>Lymphatic Metastasis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Microscopy, Electron</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - ultrastructure</subject><subject>Tumors of the skin and soft tissue. 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G</creatorcontrib><creatorcontrib>WOLFISH, P. S</creatorcontrib><creatorcontrib>HENG, M. C. Y</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of dermatopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PILGRIM, J. P</au><au>KLOSS, S. G</au><au>WOLFISH, P. S</au><au>HENG, M. C. Y</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary mucinous carcinoma of the skin with metastases to the lymph nodes</atitle><jtitle>The American journal of dermatopathology</jtitle><addtitle>Am J Dermatopathol</addtitle><date>1985-10</date><risdate>1985</risdate><volume>7</volume><issue>5</issue><spage>461</spage><epage>469</epage><pages>461-469</pages><issn>0193-1091</issn><eissn>1533-0311</eissn><coden>AJODDB</coden><abstract>Primary mucinous carcinoma is a rare sweat-gland neoplasm of the skin with a tendency to grow slowly. Although the neoplasm persists locally in nearly half of the cases after attempts at removal, metastases to regional lymph nodes and widespread metastases are uncommon. We present a case of primary mucinous carcinoma in an axilla with metastases to the axillary lymph nodes and propose a hypothesis explaining the slow rate of growth, based on our findings of a paucity of both blood vessels and macrophages in the neoplasm. Electron microscopy revealed mucin production by the dark cell and its extracellular secretion, which supports the theory of eccrine differentiation of the neoplasm.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>3004247</pmid><doi>10.1097/00000372-198510000-00011</doi><tpages>9</tpages></addata></record> |
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| identifier | ISSN: 0193-1091 |
| ispartof | The American journal of dermatopathology, 1985-10, Vol.7 (5), p.461-469 |
| issn | 0193-1091 1533-0311 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adenocarcinoma, Mucinous - pathology Adenocarcinoma, Mucinous - ultrastructure Aged Biological and medical sciences Dermatology Humans Lymph Nodes - pathology Lymph Nodes - ultrastructure Lymphatic Metastasis Male Medical sciences Microscopy, Electron Skin Neoplasms - pathology Skin Neoplasms - ultrastructure Tumors of the skin and soft tissue. Premalignant lesions |
| title | Primary mucinous carcinoma of the skin with metastases to the lymph nodes |
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