A new method to evaluate cardiovascular response in anesthetized rats hypertension after variable intensity, brief electrical stimuli

To establish and standardize a nociceptive response in anesthetized rats, the hypertensive responses to defined electrical and mechanical stimuli were studied. Rats ( n = 7) were given etomidate, 3.8 mg/kg/hr intravenously (i.v.) 2 hr following carotid artery and jugular vein cannulation. At 15 min...

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Veröffentlicht in:Journal of pharmacological and toxicological methods 1994-04, Vol.31 (2), p.99-105
Hauptverfasser: Zavisca, Frank G., David, Yadin, Kao, Y.James, Cronau, Leslie H., Stanley, Theodore H., David, Tal
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Sprache:eng
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