Transport of α-aminoisobutyric acid across the blood-brain barrier studied with in situ perfusion of rat brain

Transport of α-aminoisobutyric acid (AIB) from blood to brain in pentobarbital-anesthetized rats was examined using in situ perfusion. In situ perfusion with washed sheep red blood cells allowed the precise control of the composition of the perfusate that was necessary for a detailed examination of...

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Veröffentlicht in:	Brain research 1994-04, Vol.643 (1), p.100-107
Hauptverfasser:	Ennis, Steven R., Ren, Xiao-dan, Lorris Betz, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid Amino Acids - metabolism Aminoisobutyric Acids - metabolism Animals Biological and medical sciences Blood-brain barrier Blood-Brain Barrier - drug effects Brain Brain - blood supply Brain - metabolism Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Electroencephalography Fundamental and applied biological sciences. Psychology Kinetics Male Mathematics Models, Neurological Organ Specificity Perfusion (in situ) Perfusion - methods Permeability Phenylalanine - pharmacology Rats Rats, Sprague-Dawley Time Factors Transport Vertebrates: nervous system and sense organs α-Aminoisobutyric acid
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