Fate of allogeneic or syngeneic cells in intravenous or portal vein injection: Possible explanation for the mechanism of tolerance induction by portal vein injection

In this report we examine the fate of donor cells injected via different routes. When PKH‐26‐labeled C57BL/6 (B6) spleen cells were intravenously (i.v.) injected into BALB/c mice, the donor cells were rejected within 3 days. In contrast, when the same B6 spleen cells were portal venously (p.v.) inje...

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Veröffentlicht in:	European journal of immunology 1994-07, Vol.24 (7), p.1558-1565
Hauptverfasser:	Zhang, Yongfa, Yasumizu, Ryoji, Sugiura, Kikuya, Hashimoto, Futoshi, Amoh, Yasuo, Lian, Zhexiong, Cherry, Nishio, Nohuhiro, Ikehara, Susumu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone Marrow Cells Cell Movement - immunology Female Fluorescent Dyes Fundamental and applied biological sciences. Psychology Fundamental immunology Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells - immunology Hemopoietic stem cell Hypersensitivity, Delayed Immune Tolerance - immunology Immunization - methods Immunobiology Immunological tolerance Injections, Intravenous - methods Liver Liver - cytology Liver - immunology Mice Mice, Inbred BALB C Mice, Inbred C3H Mice, Inbred C57BL Organic Chemicals Portal Vein - immunology Spleen - cytology Thymus Gland - cytology Tolerance induction Transplantation, Homologous - immunology Transplantation, Isogeneic - immunology
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