Expression of the major surface glycoprotein of Leishmania, gp63, in wild‐type and sinefungin‐resistant promastigotes

In this study, we have surveyed gp63 expression in sinefungin‐(SF)‐resistant and wild‐type Leishmania promastigotes. Documentation of gp63 expression in Leishmania promastigotes was carried out by Western blotting, purification of the protein and assessment of gp63 protease activity. We demonstrated...

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Veröffentlicht in:	European journal of biochemistry 1994-07, Vol.223 (1), p.61-68
Hauptverfasser:	SOTERIADOU, Ketty P., TZINIA, Athina K., MAMALAKI, Avgi, PHELOUZAT, Marie‐Anne, LAWRENCE, Francoise, ROBERT‐GERO, Malka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - pharmacology Animals Antiprotozoal Agents - pharmacology Drug Resistance Endopeptidases - metabolism Leishmania - drug effects Leishmania - genetics Leishmania - metabolism Leishmania - pathogenicity Leishmania donovani Leishmania tropica Leishmaniasis - metabolism Metalloendopeptidases - genetics Metalloendopeptidases - metabolism Mice Mice, Inbred BALB C Protozoan Proteins - genetics Protozoan Proteins - metabolism RNA, Messenger - metabolism
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