Changes in the messenger ribonucleic acid for insulin-like growth factor-I and -II in the porcine testis during and between two waves of testicular development
The boar testis was used as a model for examining the possible role of production of the insulin-like growth factors (IGF) in steroidogenesis and/or testicular growth as testicular development occurs in waves. Blood and testes were sampled from boars at different ages (100-102 days of gestation; 7,...
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| Veröffentlicht in: | Biology of reproduction 1994-05, Vol.50 (5), p.993-999 |
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| creator | Clark, A.M Samaras, S.E Hammond, J.M Hagen, D.R |
| description | The boar testis was used as a model for examining the possible role of production of the insulin-like growth factors (IGF) in steroidogenesis and/or testicular growth as testicular development occurs in waves. Blood and testes were sampled from boars at different ages (100-102 days of gestation; 7, 19, and 30 days; and 10 and 25 wk), selected to occur during and between the last two waves of testicular development. Serum was analyzed for testosterone and RNA was extracted from the testes for Northern and dot-blot analysis of IGF mRNA. Testosterone concentrations declined (p = 0.01) from 7 days to 10 wk of age and rebounded at 25 wk, indicating completion of the second and third waves of testicular development. The quantity of testicular mRNA for IGF-I increased gradually with age, and that for IGF-II decreased. We therefore conclude that regulation of the expression of the mRNAs for IGF-I and -II in the pig testis is not a function of either the waves of testicular development or the level of steroidogenesis |
| doi_str_mv | 10.1095/biolreprod50.5.993 |
| format | Article |
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Blood and testes were sampled from boars at different ages (100-102 days of gestation; 7, 19, and 30 days; and 10 and 25 wk), selected to occur during and between the last two waves of testicular development. Serum was analyzed for testosterone and RNA was extracted from the testes for Northern and dot-blot analysis of IGF mRNA. Testosterone concentrations declined (p = 0.01) from 7 days to 10 wk of age and rebounded at 25 wk, indicating completion of the second and third waves of testicular development. The quantity of testicular mRNA for IGF-I increased gradually with age, and that for IGF-II decreased. We therefore conclude that regulation of the expression of the mRNAs for IGF-I and -II in the pig testis is not a function of either the waves of testicular development or the level of steroidogenesis</description><identifier>ISSN: 0006-3363</identifier><identifier>EISSN: 1529-7268</identifier><identifier>DOI: 10.1095/biolreprod50.5.993</identifier><identifier>PMID: 8025179</identifier><identifier>CODEN: BIREBV</identifier><language>eng</language><publisher>Madison, WI: Society for the Study of Reproduction</publisher><subject>Actins - genetics ; Aging ; Animals ; ARN MENSAJERO ; ARN MESSAGER ; Biological and medical sciences ; Blotting, Northern ; CASTRACION ; CASTRATION ; DESARROLLO BIOLOGICO ; DEVELOPPEMENT BIOLOGIQUE ; FACTEUR DE CROISSANCE IGF ; FACTOR DE CRECIMIENTO IGF ; Female ; Fundamental and applied biological sciences. Psychology ; Hormone metabolism and regulation ; Insulin-Like Growth Factor I - genetics ; Insulin-Like Growth Factor II - genetics ; Male ; Mammalian male genital system ; RNA, Messenger - metabolism ; Swine ; TESTICULE ; TESTICULOS ; Testis - embryology ; Testis - growth & development ; Testis - metabolism ; Uterus - metabolism ; VERRACO ; VERRAT ; Vertebrates: reproduction</subject><ispartof>Biology of reproduction, 1994-05, Vol.50 (5), p.993-999</ispartof><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4092437$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8025179$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Clark, A.M</creatorcontrib><creatorcontrib>Samaras, S.E</creatorcontrib><creatorcontrib>Hammond, J.M</creatorcontrib><creatorcontrib>Hagen, D.R</creatorcontrib><title>Changes in the messenger ribonucleic acid for insulin-like growth factor-I and -II in the porcine testis during and between two waves of testicular development</title><title>Biology of reproduction</title><addtitle>Biol Reprod</addtitle><description>The boar testis was used as a model for examining the possible role of production of the insulin-like growth factors (IGF) in steroidogenesis and/or testicular growth as testicular development occurs in waves. Blood and testes were sampled from boars at different ages (100-102 days of gestation; 7, 19, and 30 days; and 10 and 25 wk), selected to occur during and between the last two waves of testicular development. Serum was analyzed for testosterone and RNA was extracted from the testes for Northern and dot-blot analysis of IGF mRNA. Testosterone concentrations declined (p = 0.01) from 7 days to 10 wk of age and rebounded at 25 wk, indicating completion of the second and third waves of testicular development. The quantity of testicular mRNA for IGF-I increased gradually with age, and that for IGF-II decreased. We therefore conclude that regulation of the expression of the mRNAs for IGF-I and -II in the pig testis is not a function of either the waves of testicular development or the level of steroidogenesis</description><subject>Actins - genetics</subject><subject>Aging</subject><subject>Animals</subject><subject>ARN MENSAJERO</subject><subject>ARN MESSAGER</subject><subject>Biological and medical sciences</subject><subject>Blotting, Northern</subject><subject>CASTRACION</subject><subject>CASTRATION</subject><subject>DESARROLLO BIOLOGICO</subject><subject>DEVELOPPEMENT BIOLOGIQUE</subject><subject>FACTEUR DE CROISSANCE IGF</subject><subject>FACTOR DE CRECIMIENTO IGF</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hormone metabolism and regulation</subject><subject>Insulin-Like Growth Factor I - genetics</subject><subject>Insulin-Like Growth Factor II - genetics</subject><subject>Male</subject><subject>Mammalian male genital system</subject><subject>RNA, Messenger - metabolism</subject><subject>Swine</subject><subject>TESTICULE</subject><subject>TESTICULOS</subject><subject>Testis - embryology</subject><subject>Testis - growth & development</subject><subject>Testis - metabolism</subject><subject>Uterus - metabolism</subject><subject>VERRACO</subject><subject>VERRAT</subject><subject>Vertebrates: reproduction</subject><issn>0006-3363</issn><issn>1529-7268</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo90c1u1DAQB3ALgcq28AKVkHyA3rLYcRzHR7TiY6VKHKDnaOJMEoNjL3bSiKfhVTHswsnSzE__sceE3HK250zLt50NLuIphl6yvdxrLZ6QHZelLlRZN0_JjjFWF0LU4jm5TukbY7wSpbgiVw0rJVd6R34dJvAjJmo9XSakM6aEuRBptF3wq3FoDQVjezqEmFVanfWFs9-RjjFsy0QHMEuIxZGC72lxPP6LOoVorEe6YFpsov0arR__og6XDTGrLdANHvP0MJyZWR1E2uMjunCa0S8vyLMBXMKXl_OGPHx4__Xwqbj__PF4eHdfDFzrpZB6UDI_jtdNV0neAPS8GWoUKCSTQjUd12VnBChRl7Xq2FBC16vecA3KQCluyN05N2_zx5qv0s42GXQOPIY1taqWqqlrleGrC1y7Gfv2FO0M8Wd72Wjuv770IRlwQwRvbPrPKqbLSvyJeXNmkx2nzUZs0wzO5VDRbtsmWSvb_J_Z3Z7dAKGFMeaohy9asqrSjfgNKGieuQ</recordid><startdate>199405</startdate><enddate>199405</enddate><creator>Clark, A.M</creator><creator>Samaras, S.E</creator><creator>Hammond, J.M</creator><creator>Hagen, D.R</creator><general>Society for the Study of Reproduction</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199405</creationdate><title>Changes in the messenger ribonucleic acid for insulin-like growth factor-I and -II in the porcine testis during and between two waves of testicular development</title><author>Clark, A.M ; Samaras, S.E ; Hammond, J.M ; Hagen, D.R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-f199t-59f75143168b4518aad18f6e3e3505378b192bc3a736267b0f2abd7dc19a7ca23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Actins - genetics</topic><topic>Aging</topic><topic>Animals</topic><topic>ARN MENSAJERO</topic><topic>ARN MESSAGER</topic><topic>Biological and medical sciences</topic><topic>Blotting, Northern</topic><topic>CASTRACION</topic><topic>CASTRATION</topic><topic>DESARROLLO BIOLOGICO</topic><topic>DEVELOPPEMENT BIOLOGIQUE</topic><topic>FACTEUR DE CROISSANCE IGF</topic><topic>FACTOR DE CRECIMIENTO IGF</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hormone metabolism and regulation</topic><topic>Insulin-Like Growth Factor I - genetics</topic><topic>Insulin-Like Growth Factor II - genetics</topic><topic>Male</topic><topic>Mammalian male genital system</topic><topic>RNA, Messenger - metabolism</topic><topic>Swine</topic><topic>TESTICULE</topic><topic>TESTICULOS</topic><topic>Testis - embryology</topic><topic>Testis - growth & development</topic><topic>Testis - metabolism</topic><topic>Uterus - metabolism</topic><topic>VERRACO</topic><topic>VERRAT</topic><topic>Vertebrates: reproduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Clark, A.M</creatorcontrib><creatorcontrib>Samaras, S.E</creatorcontrib><creatorcontrib>Hammond, J.M</creatorcontrib><creatorcontrib>Hagen, D.R</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Biology of reproduction</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Clark, A.M</au><au>Samaras, S.E</au><au>Hammond, J.M</au><au>Hagen, D.R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Changes in the messenger ribonucleic acid for insulin-like growth factor-I and -II in the porcine testis during and between two waves of testicular development</atitle><jtitle>Biology of reproduction</jtitle><addtitle>Biol Reprod</addtitle><date>1994-05</date><risdate>1994</risdate><volume>50</volume><issue>5</issue><spage>993</spage><epage>999</epage><pages>993-999</pages><issn>0006-3363</issn><eissn>1529-7268</eissn><coden>BIREBV</coden><abstract>The boar testis was used as a model for examining the possible role of production of the insulin-like growth factors (IGF) in steroidogenesis and/or testicular growth as testicular development occurs in waves. Blood and testes were sampled from boars at different ages (100-102 days of gestation; 7, 19, and 30 days; and 10 and 25 wk), selected to occur during and between the last two waves of testicular development. Serum was analyzed for testosterone and RNA was extracted from the testes for Northern and dot-blot analysis of IGF mRNA. Testosterone concentrations declined (p = 0.01) from 7 days to 10 wk of age and rebounded at 25 wk, indicating completion of the second and third waves of testicular development. The quantity of testicular mRNA for IGF-I increased gradually with age, and that for IGF-II decreased. We therefore conclude that regulation of the expression of the mRNAs for IGF-I and -II in the pig testis is not a function of either the waves of testicular development or the level of steroidogenesis</abstract><cop>Madison, WI</cop><pub>Society for the Study of Reproduction</pub><pmid>8025179</pmid><doi>10.1095/biolreprod50.5.993</doi><tpages>7</tpages></addata></record> |
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| ispartof | Biology of reproduction, 1994-05, Vol.50 (5), p.993-999 |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Actins - genetics Aging Animals ARN MENSAJERO ARN MESSAGER Biological and medical sciences Blotting, Northern CASTRACION CASTRATION DESARROLLO BIOLOGICO DEVELOPPEMENT BIOLOGIQUE FACTEUR DE CROISSANCE IGF FACTOR DE CRECIMIENTO IGF Female Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation Insulin-Like Growth Factor I - genetics Insulin-Like Growth Factor II - genetics Male Mammalian male genital system RNA, Messenger - metabolism Swine TESTICULE TESTICULOS Testis - embryology Testis - growth & development Testis - metabolism Uterus - metabolism VERRACO VERRAT Vertebrates: reproduction |
| title | Changes in the messenger ribonucleic acid for insulin-like growth factor-I and -II in the porcine testis during and between two waves of testicular development |
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