Renal Microvascular Responses to Sepsis Are Dependent on Nitric Oxide

Nitric oxide (NO) is an important mediator of the hemodynamic response to sepsis; however, its visceral microcirculatory effects are largely unknown. To determine the role of NO in renal microvascular responses to bacteremia, rat hydronephrotic kidneys with intact neurovascular supplies were exterio...

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Veröffentlicht in:	The Journal of surgical research 1994-06, Vol.56 (6), p.524-529
Hauptverfasser:	Spain, David A., Wilson, Mark A., Bloom, Ian T.M., Garrison, R.Neal
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine - analogs & derivatives Arginine - pharmacology Bacteremia - physiopathology Biological and medical sciences Escherichia coli Infections - physiopathology General aspects Infection pathogenesis Infectious diseases Male Medical sciences Microcirculation NG-Nitroarginine Methyl Ester Nitric Oxide - antagonists & inhibitors Nitric Oxide - physiology Rats Rats, Sprague-Dawley Renal Circulation - drug effects Vasoconstriction
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