Projections of the rat trigeminal sensory nuclear complex demonstrated by multiple fluorescent dye retrograde transport
The fluorescent dyes True Blue, Fast Blue, Nuclear Yellow and SITS were used to examine the connections of the rat brainstem sensory trigeminal nuclear complex (nV). Particular attention was paid to the following questions: do individual trigeminal neurons project to multiple targets via axon collat...
Gespeichert in:
Veröffentlicht in: | Brain research 1985-12, Vol.361 (1), p.383-388 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 388 |
---|---|
container_issue | 1 |
container_start_page | 383 |
container_title | Brain research |
container_volume | 361 |
creator | Silverman, James D. Kruger, Lawrence |
description | The fluorescent dyes True Blue, Fast Blue, Nuclear Yellow and SITS were used to examine the connections of the rat brainstem sensory trigeminal nuclear complex (nV). Particular attention was paid to the following questions: do individual trigeminal neurons project to multiple targets via axon collaterals; and do primary afferent inputs to the various regions of nV arise from individual cells? Pairs of injections, using contrasting dyes, were made into the following target area combinations: ventrobasal thalamus-ipsilateral superior colliculus, cerebellum-contralateral thalamus, nucleus principalis of nV-contralateral thalamus, and nucleus principalis of nV-subnucleus caudalis of spinal nV. In general, numerous neurons throughout all subdivisions of nV and within the trigeminal ganglion were labeled by a single dye following the injections. In addition, many cells in a similar distribution were found to be doubly-labeled following such injection combination. These data demonstrate the existence of significant subpopulations of first- and second-order neurons that project to multiple targets via divergent axonal ramifications throughout the rat sensory trigeminal system. |
doi_str_mv | 10.1016/0006-8993(85)91308-3 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76566679</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0006899385913083</els_id><sourcerecordid>76566679</sourcerecordid><originalsourceid>FETCH-LOGICAL-c483t-955b3e85b6537aba9eac6cc25949a1b9fc7bf14e4f99d2a047e171f78814d9413</originalsourceid><addsrcrecordid>eNqFkU2LFDEYhIO4rOPqP1DIQUQPrUknnY_Lgix-LCysBz2HdPL2miXdGZO0Ov_ejDPM0T2FUE8VL1UIvaDkHSVUvCeEiE5pzd6o4a2mjKiOPUIbqmTfiZ6Tx2hzQp6gp6Xcty9jmpyj855TKQTboN9fc7oHV0NaCk4Trj8AZ1txzeEO5rDYiAssJeUdXlYXwWbs0ryN8Ad7mJupNho8Hnd4XmMNTcFTXFOG4mCp2O9aHtSc7rL10GLtUrYp12fobLKxwPPje4G-f_r47epLd3P7-frqw03nuGK108MwMlDDKAYm7Wg1WCec6wfNtaWjnpwcJ8qBT1r73hIugUo6SaUo95pTdoFeH3K3Of1coVQzh3ZZjHaBtBYjxSCEkPpBkHKuBqZFA_kBdDmVkmEy2xxmm3eGErMfxuxbN_vWjRrMv2EMa7aXx_x1nMGfTMclmv7qqNvibJxaUS6UE6YE1VL1Dbs8YNBK-xUgm-ICLA58yG1G41P4_x1_AT_qrIk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14485396</pqid></control><display><type>article</type><title>Projections of the rat trigeminal sensory nuclear complex demonstrated by multiple fluorescent dye retrograde transport</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Silverman, James D. ; Kruger, Lawrence</creator><creatorcontrib>Silverman, James D. ; Kruger, Lawrence</creatorcontrib><description>The fluorescent dyes True Blue, Fast Blue, Nuclear Yellow and SITS were used to examine the connections of the rat brainstem sensory trigeminal nuclear complex (nV). Particular attention was paid to the following questions: do individual trigeminal neurons project to multiple targets via axon collaterals; and do primary afferent inputs to the various regions of nV arise from individual cells? Pairs of injections, using contrasting dyes, were made into the following target area combinations: ventrobasal thalamus-ipsilateral superior colliculus, cerebellum-contralateral thalamus, nucleus principalis of nV-contralateral thalamus, and nucleus principalis of nV-subnucleus caudalis of spinal nV. In general, numerous neurons throughout all subdivisions of nV and within the trigeminal ganglion were labeled by a single dye following the injections. In addition, many cells in a similar distribution were found to be doubly-labeled following such injection combination. These data demonstrate the existence of significant subpopulations of first- and second-order neurons that project to multiple targets via divergent axonal ramifications throughout the rat sensory trigeminal system.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/0006-8993(85)91308-3</identifier><identifier>PMID: 2417663</identifier><identifier>CODEN: BRREAP</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Anatomy ; Animals ; Axonal Transport ; Axons - physiology ; Biological and medical sciences ; Brain Stem - anatomy & histology ; Central nervous system ; cerebellum ; Efferent Pathways - anatomy & histology ; fluorescent dye ; Fluorescent Dyes ; Fundamental and applied biological sciences. Psychology ; midbrain ; Neurons - physiology ; rat ; Rats ; Rats, Inbred Strains ; thalamus ; Trigeminal Nuclei - anatomy & histology ; trigeminal sensory system ; Vertebrates: nervous system and sense organs</subject><ispartof>Brain research, 1985-12, Vol.361 (1), p.383-388</ispartof><rights>1985 Elsevier Science Publishers B.V. (Biomedical Division)</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-955b3e85b6537aba9eac6cc25949a1b9fc7bf14e4f99d2a047e171f78814d9413</citedby><cites>FETCH-LOGICAL-c483t-955b3e85b6537aba9eac6cc25949a1b9fc7bf14e4f99d2a047e171f78814d9413</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0006-8993(85)91308-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27929,27930,46000</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8619782$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2417663$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silverman, James D.</creatorcontrib><creatorcontrib>Kruger, Lawrence</creatorcontrib><title>Projections of the rat trigeminal sensory nuclear complex demonstrated by multiple fluorescent dye retrograde transport</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>The fluorescent dyes True Blue, Fast Blue, Nuclear Yellow and SITS were used to examine the connections of the rat brainstem sensory trigeminal nuclear complex (nV). Particular attention was paid to the following questions: do individual trigeminal neurons project to multiple targets via axon collaterals; and do primary afferent inputs to the various regions of nV arise from individual cells? Pairs of injections, using contrasting dyes, were made into the following target area combinations: ventrobasal thalamus-ipsilateral superior colliculus, cerebellum-contralateral thalamus, nucleus principalis of nV-contralateral thalamus, and nucleus principalis of nV-subnucleus caudalis of spinal nV. In general, numerous neurons throughout all subdivisions of nV and within the trigeminal ganglion were labeled by a single dye following the injections. In addition, many cells in a similar distribution were found to be doubly-labeled following such injection combination. These data demonstrate the existence of significant subpopulations of first- and second-order neurons that project to multiple targets via divergent axonal ramifications throughout the rat sensory trigeminal system.</description><subject>Anatomy</subject><subject>Animals</subject><subject>Axonal Transport</subject><subject>Axons - physiology</subject><subject>Biological and medical sciences</subject><subject>Brain Stem - anatomy & histology</subject><subject>Central nervous system</subject><subject>cerebellum</subject><subject>Efferent Pathways - anatomy & histology</subject><subject>fluorescent dye</subject><subject>Fluorescent Dyes</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>midbrain</subject><subject>Neurons - physiology</subject><subject>rat</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>thalamus</subject><subject>Trigeminal Nuclei - anatomy & histology</subject><subject>trigeminal sensory system</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2LFDEYhIO4rOPqP1DIQUQPrUknnY_Lgix-LCysBz2HdPL2miXdGZO0Ov_ejDPM0T2FUE8VL1UIvaDkHSVUvCeEiE5pzd6o4a2mjKiOPUIbqmTfiZ6Tx2hzQp6gp6Xcty9jmpyj855TKQTboN9fc7oHV0NaCk4Trj8AZ1txzeEO5rDYiAssJeUdXlYXwWbs0ryN8Ad7mJupNho8Hnd4XmMNTcFTXFOG4mCp2O9aHtSc7rL10GLtUrYp12fobLKxwPPje4G-f_r47epLd3P7-frqw03nuGK108MwMlDDKAYm7Wg1WCec6wfNtaWjnpwcJ8qBT1r73hIugUo6SaUo95pTdoFeH3K3Of1coVQzh3ZZjHaBtBYjxSCEkPpBkHKuBqZFA_kBdDmVkmEy2xxmm3eGErMfxuxbN_vWjRrMv2EMa7aXx_x1nMGfTMclmv7qqNvibJxaUS6UE6YE1VL1Dbs8YNBK-xUgm-ICLA58yG1G41P4_x1_AT_qrIk</recordid><startdate>19851230</startdate><enddate>19851230</enddate><creator>Silverman, James D.</creator><creator>Kruger, Lawrence</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19851230</creationdate><title>Projections of the rat trigeminal sensory nuclear complex demonstrated by multiple fluorescent dye retrograde transport</title><author>Silverman, James D. ; Kruger, Lawrence</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-955b3e85b6537aba9eac6cc25949a1b9fc7bf14e4f99d2a047e171f78814d9413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Anatomy</topic><topic>Animals</topic><topic>Axonal Transport</topic><topic>Axons - physiology</topic><topic>Biological and medical sciences</topic><topic>Brain Stem - anatomy & histology</topic><topic>Central nervous system</topic><topic>cerebellum</topic><topic>Efferent Pathways - anatomy & histology</topic><topic>fluorescent dye</topic><topic>Fluorescent Dyes</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>midbrain</topic><topic>Neurons - physiology</topic><topic>rat</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>thalamus</topic><topic>Trigeminal Nuclei - anatomy & histology</topic><topic>trigeminal sensory system</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Silverman, James D.</creatorcontrib><creatorcontrib>Kruger, Lawrence</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Silverman, James D.</au><au>Kruger, Lawrence</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Projections of the rat trigeminal sensory nuclear complex demonstrated by multiple fluorescent dye retrograde transport</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1985-12-30</date><risdate>1985</risdate><volume>361</volume><issue>1</issue><spage>383</spage><epage>388</epage><pages>383-388</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><coden>BRREAP</coden><abstract>The fluorescent dyes True Blue, Fast Blue, Nuclear Yellow and SITS were used to examine the connections of the rat brainstem sensory trigeminal nuclear complex (nV). Particular attention was paid to the following questions: do individual trigeminal neurons project to multiple targets via axon collaterals; and do primary afferent inputs to the various regions of nV arise from individual cells? Pairs of injections, using contrasting dyes, were made into the following target area combinations: ventrobasal thalamus-ipsilateral superior colliculus, cerebellum-contralateral thalamus, nucleus principalis of nV-contralateral thalamus, and nucleus principalis of nV-subnucleus caudalis of spinal nV. In general, numerous neurons throughout all subdivisions of nV and within the trigeminal ganglion were labeled by a single dye following the injections. In addition, many cells in a similar distribution were found to be doubly-labeled following such injection combination. These data demonstrate the existence of significant subpopulations of first- and second-order neurons that project to multiple targets via divergent axonal ramifications throughout the rat sensory trigeminal system.</abstract><cop>London</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>2417663</pmid><doi>10.1016/0006-8993(85)91308-3</doi><tpages>6</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0006-8993 |
ispartof | Brain research, 1985-12, Vol.361 (1), p.383-388 |
issn | 0006-8993 1872-6240 |
language | eng |
recordid | cdi_proquest_miscellaneous_76566679 |
source | MEDLINE; Elsevier ScienceDirect Journals Complete |
subjects | Anatomy Animals Axonal Transport Axons - physiology Biological and medical sciences Brain Stem - anatomy & histology Central nervous system cerebellum Efferent Pathways - anatomy & histology fluorescent dye Fluorescent Dyes Fundamental and applied biological sciences. Psychology midbrain Neurons - physiology rat Rats Rats, Inbred Strains thalamus Trigeminal Nuclei - anatomy & histology trigeminal sensory system Vertebrates: nervous system and sense organs |
title | Projections of the rat trigeminal sensory nuclear complex demonstrated by multiple fluorescent dye retrograde transport |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T08%3A24%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Projections%20of%20the%20rat%20trigeminal%20sensory%20nuclear%20complex%20demonstrated%20by%20multiple%20fluorescent%20dye%20retrograde%20transport&rft.jtitle=Brain%20research&rft.au=Silverman,%20James%20D.&rft.date=1985-12-30&rft.volume=361&rft.issue=1&rft.spage=383&rft.epage=388&rft.pages=383-388&rft.issn=0006-8993&rft.eissn=1872-6240&rft.coden=BRREAP&rft_id=info:doi/10.1016/0006-8993(85)91308-3&rft_dat=%3Cproquest_cross%3E76566679%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=14485396&rft_id=info:pmid/2417663&rft_els_id=0006899385913083&rfr_iscdi=true |