Functional neuronal ionotropic glutamate receptors are expressed in the non-neuronal cell line MIN6

We report that a non-neuronal cell line, MIN6, derived from insulin-secreting pancreatic beta-cells, naturally expresses functional ionotropic glutamate receptors. Electrophysiological recordings show that kainate, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and N-methyl-D-aspartat...

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Veröffentlicht in:	The Journal of biological chemistry 1994-06, Vol.269 (25), p.16989-16992
Hauptverfasser:	GONOI, T, MIZUNO, N, INAGAKI, N, KUROMI, H, SEINO, Y, MIYAZAKI, J.-I, SEINO, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoacid receptors (glycine, glutamate, gaba) Animals Base Sequence Biological and medical sciences Calcium - metabolism Cell Line Cell receptors Cell structures and functions DNA Primers - chemistry Fundamental and applied biological sciences. Psychology Gene Expression Insulin - metabolism Insulin Secretion Islets of Langerhans - metabolism Membrane Potentials Mice Molecular and cellular biology Molecular Sequence Data Receptors, Glutamate - metabolism Receptors, Kainic Acid - metabolism Receptors, N-Methyl-D-Aspartate - metabolism RNA, Messenger - genetics Signal Transduction
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