Cellular Activation of Thromboxane Receptors

Thromboxane A2 is an abundant and potent product of arachidonic acid metabolism in human platelets. Its clinical importance is highlighted by the efficacy of aspirin, which, due to its irreversible inhibition of the enzyme PGG/H synthase, selects the anucleate platelet as a particular target for ext...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 1994-04, Vol.714 (1), p.270-278
Hauptverfasser:	KINSELLA, B. THERESE, O'MAHONY, DANIEL J., LAWSON, JOHN A., PRATICO, DOMENICO, FITZGERALD, GARRET A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Blood Platelets - physiology Humans Molecular Sequence Data Muscle, Smooth, Vascular - physiology Point Mutation Polymorphism, Genetic Receptors, Eicosanoid - genetics Receptors, Eicosanoid - physiology Receptors, Thromboxane - biosynthesis Receptors, Thromboxane - genetics Receptors, Thromboxane - metabolism
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