Comparison of the effects of hydralazine on tumor and normal tissue blood perfusion by MRI

Purpose : The differential effects on blood perfusion of the vasodilator hydralazine (HYD) between tumor and normal muscle have been measured using the dynamic enhanced-magnetic resonance imaging (DE-MRI) technique. Methods and Materials : DE-MRI is a noninvasive method of determining blood perfusio...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 1994-06, Vol.29 (3), p.473-479
Hauptverfasser:	Belfi, Charles A., Paul, Chitta R., Shan, Siqing, Ngo, Frank Q.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Chemotherapy Dose-Response Relationship, Drug Dynamic MRI Gadolinium DTPA Gd-DTPA Hydralazine Hydralazine - pharmacology KHT sarcoma Magnetic Resonance Imaging Magnetic resonance imaging (MRI) Medical sciences Mice Mice, Inbred C3H Muscle blood perfusion Muscles - blood supply Organometallic Compounds Pentetic Acid - analogs & derivatives Pharmacology. Drug treatments Regional Blood Flow - drug effects Sarcoma, Experimental - blood supply Tumor blood perfusion
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