Age-related basement membrane thickening of the vocal cords in sudden infant death syndrome (SIDS)

Sudden infant death syndrome (SIDS) remains the leading cause of death in the Western world among infants between the ages of 1 month to 1 year. The diagnosis can only be established at autopsy, at which time no obvious or recognizable pathology is evident. A correlation between thickening of the ba...

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Veröffentlicht in:The Laryngoscope 1994-07, Vol.104 (7), p.865-868
Hauptverfasser: Shatz, Anat, Arensburg, Baruch, Hiss, Yehuda, Hammel, Ilan, Variend, Sadik
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container_end_page 868
container_issue 7
container_start_page 865
container_title The Laryngoscope
container_volume 104
creator Shatz, Anat
Arensburg, Baruch
Hiss, Yehuda
Hammel, Ilan
Variend, Sadik
description Sudden infant death syndrome (SIDS) remains the leading cause of death in the Western world among infants between the ages of 1 month to 1 year. The diagnosis can only be established at autopsy, at which time no obvious or recognizable pathology is evident. A correlation between thickening of the basement membrane of the true vocal cords and the victim's age was observed in all 51 larynges examined, whereas no such finding was detected in 82 larynges of infants who died of other causes. Thus, the data support the authors' previous morphological results suggesting the use of basement membrane thickening as a marker of positive diagnosis of SIDS at autopsy. The possibility that an immune process may be associated with this syndrome merits further investigation and could prove to be of great importance.
doi_str_mv 10.1288/00005537-199407000-00016
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subjects Age Factors
Basement Membrane - pathology
Biological and medical sciences
Cadaver
Double-Blind Method
Epithelium - pathology
Humans
Infant
Medical sciences
Non tumoral diseases
Otorhinolaryngology. Stomatology
Regression Analysis
Sudden Infant Death - pathology
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
Vocal Cords - pathology
title Age-related basement membrane thickening of the vocal cords in sudden infant death syndrome (SIDS)
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