Differential regulation of the 2′,3′-cyclic nucleotide 3′-phosphodiesterase gene during oligodendrocyte development

The two major isoforms of 2′,3′-cyclic nucleotide phosphodiesterase (CNP), 48 and 46 kDa, have recently been shown to be produced from a single gene by alternative splicing. In addition, messenger RNA encoding the larger isoform is transcribed from a separate promoter, approximately 1 kb upstream fr...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 1994-06, Vol.12 (6), p.1363-1375
Hauptverfasser:	Scherer, Steven S., Braun, Peter E., Grinspan, Judith, Collarini, Ellen, Wang, D.-y., Kamholz, John
Format:	Artikel
Sprache:	eng
Schlagworte:	2',3'-Cyclic-Nucleotide Phosphodiesterases - biosynthesis Aging - metabolism Animals Blotting, Northern Blotting, Western Brain - enzymology Brain - growth & development Cells, Cultured Gene Expression Regulation, Enzymologic Humans Immunohistochemistry In Situ Hybridization Isoenzymes - biosynthesis Neurons - enzymology Oligodendroglia - drug effects Oligodendroglia - enzymology Optic Nerve - enzymology Optic Nerve - growth & development Platelet-Derived Growth Factor - pharmacology Promoter Regions, Genetic Rats Rats, Sprague-Dawley RNA, Messenger - analysis RNA, Messenger - biosynthesis Transcription, Genetic
Online-Zugang:	Volltext
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