An Improved Method for Isolation of Mutator Mutants from Mouse FM3A Cells and Their Characterization

An improved method to select mutator mutants was de-veloped. By this new method, mutator mutants were isolated efficiently, and 7 mutants were obtained from cultured mouse FM3A cells. These mutator mutants have an elevated rate of spontaneous mutation at 3 genetic loci (resistance to ouabain, blasti...

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Veröffentlicht in:	Cell Structure and Function 1985, Vol.10(4), pp.383-390
Hauptverfasser:	Hyodo, Masao, Ito, Narushi, Yamashita, Midori, Suzuki, Kenshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aphidicolin Cell Line Cell Separation - methods Cytarabine - pharmacology Diterpenes - pharmacology DNA Replication - drug effects Guanidines - pharmacology Mammary Neoplasms, Experimental - genetics Mammary Neoplasms, Experimental - pathology Mice Mutation Nucleosides Ouabain - pharmacology Thioguanine - pharmacology Tunicamycin - pharmacology
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