Metastasis-associated mts1 gene expression correlates with increased p53 detection in the B16 murine melanoma

MTS1 is a metastasis-associated gene highly expressed in high-metastasis tumors. Here we show that the expression of the suppressor gene p53 protein correlates with mts1 expression. In murine melanoma B16-F1 cells, alpha-melanocyte-stimulating hormone up-regulated mts1 and increased p53 positivity i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	DNA and cell biology 1994-04, Vol.13 (4), p.343-351
Hauptverfasser:	PARKER, C, LAKSHMI, M. S, PIURA, B, SHERBET, G. V
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Calcium-Binding Proteins - genetics Cell Cycle - drug effects Dermatology Gene Expression - drug effects Medical sciences Melanocyte-Stimulating Hormones - pharmacology Melanoma - genetics Neoplasm Metastasis - genetics Paclitaxel - pharmacology S100 Proteins Tretinoin - pharmacology Tumor Cells, Cultured Tumor Suppressor Protein p53 - genetics Tumors of the skin and soft tissue. Premalignant lesions
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!