Monoclonal IgM in a patient with paraproteinemic polyneuropathy binds to gangliosides containing disialosyl groups

Monoclonal IgM K from a patient with polyneuropathy associated with paraproteinemia was found to bind to several polysialogangliosides. Binding of IgM to gangliosides was shown by enzyme‐linked immunosorbent assay (ELISA) and by overlaying thin‐layer chromatograms of human brain and peripheral nerve...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Annals of neurology 1985-12, Vol.18 (6), p.655-659
Hauptverfasser:	Ilyas, Amjad A., Quarles, Richard H., Dalakas, Marinos C., Fishman, Peter H., Brady, Roscoe O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Brain Chemistry Chemical Phenomena Chemistry Epitopes - analysis Gangliosides - isolation & purification Humans Immunodeficiencies. Immunoglobulinopathies Immunoglobulin M Immunoglobulinopathies Immunopathology Male Medical sciences Middle Aged Paraproteinemias - blood Paraproteins Peripheral Nerves - analysis Peripheral Nervous System Diseases - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!