IgM antibody to a hepatitis C virus core peptide (CP14) for monitoring activity of liver disease in patients with acute or chronic hepatitis C

Antibodies to the hepatitis C virus (HCV) core of various immunoglobulin classes were determined by enzyme immunoassays with three synthetic peptides, CP14 (amino acids 5‐40 of the core protein), CP10 (5‐23), and CP9 (39‐74). In 135 patients with chronic type C liver disease, anti‐CPU, anti‐CP10, an...

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Veröffentlicht in:	Journal of medical virology 1994-03, Vol.42 (3), p.311-317
Hauptverfasser:	Nagayama, Ryozo, Miyake, Kazuhiko, Tsuda, Fumio, Okamoto, Hiroaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Amino Acid Sequence Antigens, Viral - immunology Biological and medical sciences capsid proteins Carcinoma, Hepatocellular - blood Carcinoma, Hepatocellular - immunology Carcinoma, Hepatocellular - microbiology Carrier State - blood Carrier State - immunology Carrier State - microbiology Epitopes - immunology Female Hepacivirus - immunology hepatitis antibodies Hepatitis Antibodies - blood Hepatitis Antibodies - immunology hepatitis C Hepatitis C - blood Hepatitis C - immunology Hepatitis C - therapy Hepatitis C Antibodies Hepatitis C Antigens hepatitis C virus Hepatitis, Chronic - blood Hepatitis, Chronic - immunology Hepatitis, Chronic - microbiology Hepatitis, Chronic - therapy Human viral diseases Humans Immunoglobulin A - blood Immunoglobulin A - immunology Immunoglobulin G - blood Immunoglobulin G - immunology Immunoglobulin M - blood Immunoglobulin M - immunology Immunologic Factors - therapeutic use Infectious diseases Interferon alpha-2 Interferon-alpha - therapeutic use interferons Liver Cirrhosis - blood Liver Cirrhosis - immunology Liver Cirrhosis - microbiology Liver Neoplasms - blood Liver Neoplasms - immunology Liver Neoplasms - microbiology Male Medical sciences Molecular Sequence Data Monitoring, Immunologic Peptide Fragments - chemical synthesis Peptide Fragments - immunology Recombinant Proteins Treatment Outcome Viral Core Proteins - immunology Viral diseases Viral hepatitis
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