NADPH and «cocktails» containing polyarginine reactivate superoxide generation in leukocytes lysed by membrane-damaging agents

Human blood leukocytes generated large amounts of superoxide (O2-) following stimulation by certain "cocktails" of soluble agents consisting of poly-L-arginine (PARG), phytohemagglutinin, the chemotactic peptide formyl-methionyl-leucyl-phenylalanine and polyanethole sulfanote (liquoid). A...

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Veröffentlicht in:	Inflammation 1985-12, Vol.9 (4), p.341-363
Hauptverfasser:	GINSBURG, I, BORINSKI, R, PABST, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Membrane - enzymology Cytochalasins - pharmacology Digitonin - pharmacology Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Ligands Luminescent Measurements Lysophosphatidylcholines - pharmacology Myeloid cells: ontogeny, maturation, markers, receptors N-Formylmethionine Leucyl-Phenylalanine - pharmacology NADH, NADPH Oxidoreductases - metabolism NADH, NADPH Oxidoreductases - pharmacology NADPH Oxidases Neutrophils - enzymology Peptides - pharmacology Phytohemagglutinins - pharmacology Saponins - pharmacology Superoxides - metabolism
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