Insulin-like Growth Factors and Bone: The Osteoporosis Connection

Abstract In the last five years significant progress has been made defining the role of insulin-like growth factors (IGFs) in the process of bone remodeling. In this paper, we present critical evidence that IGF-I and IGF-II are produced by bone cells and regulate specific osteoblastic and osteoclast...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1994-06, Vol.206 (2), p.83-102
Hauptverfasser:	Rosen, Clifford J., Donahue, Leah Rae, Hunter, Susan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone and Bones - physiology Carrier Proteins - physiology Endopeptidases - physiology Humans Insulin-Like Growth Factor I - physiology Insulin-Like Growth Factor II - physiology Osteoporosis - physiopathology Osteoporosis - therapy
Online-Zugang:	Volltext
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