Chromosome aberrations in adenomas of the colon. Proof of trisomy 7 in tumor cells by combined interphase cytogenetics and immunocytochemistry

Thirty‐five colon adenomas from 26 patients were analyzed with centromeric probes for chromosomes 1,7, 17, X and Y in order to study numerical aberrations, chromosome imbalances, aneuploidy and tetraploidization. The fluorescent in situ hybridization (FISH) technique was applied to single‐cell suspe...

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Veröffentlicht in:	International journal of cancer 1994-06, Vol.57 (6), p.781-785
Hauptverfasser:	Herbergs, J., de Bruïne, A. P., Marx, P. T. J., Vallinga, M. I. J., Stockbrügger, R. W., Ramaekers, F. C. S., Arends, J. W., Hopman, A. H. N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - genetics Adenoma - pathology Adult Aged Biological and medical sciences Chromosome Aberrations - genetics Chromosomes, Human, Pair 7 Colonic Neoplasms - genetics Colonic Neoplasms - pathology Digestive system Female Humans In Situ Hybridization, Fluorescence Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Trisomy
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