Unique Epitope of Apolipoprotein A-I Expressed in Pre-.beta.-1 High-Density Lipoprotein and Its Role in the Catalyzed Efflux of Cellular Cholesterol

The ability of mouse anti-apolipoprotein A-I (apo A-I) monoclonal antibodies to recognize pre-beta-HDL species in native plasma was determined. An antibody identifying residues 137-144 of the mature protein uniquely recognized pre-beta-1 HDL, an HDL species of low molecular weight implicated in earl...

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Veröffentlicht in:	Biochemistry (Easton) 1994-06, Vol.33 (22), p.6981-6985
Hauptverfasser:	Fielding, Phoebe E, Kawano, Mikihiko, Catapano, Alberico L, Zoppo, Adele, Marcovina, Santica, Fielding, Christopher J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antibodies, Monoclonal ANTICORPS MONOCLONAL ANTICUERPOS MONOCLONALES ANTIGENE ANTIGENOS Apolipoprotein A-I - chemistry Apolipoprotein A-I - immunology Catalysis Cells, Cultured CHOLESTEROL Cholesterol - metabolism COLESTEROL Epitopes - analysis FIBROBLASTE FIBROBLASTOS Fibroblasts - metabolism High-Density Lipoproteins, Pre-beta Humans LIPOPROTEINAS LIPOPROTEINE Lipoproteins, HDL - chemistry Lipoproteins, HDL - immunology Lipoproteins, HDL - physiology MEMBRANAS CELULARES MEMBRANE CELLULAIRE Molecular Sequence Data RATON SOURIS
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