A Novel Technique for the One-Step Preparation of Liposomes and Nonionic Surfactant Vesicles without the Use of Organic Solvents. Liposome Formation in a Continuous Gas Stream: The ‘Bubble’ Method

A novel technique for the preparation of liposomes without the use of organic solvents, detergents, or high shear forces is described. Introduction of inert gas bubbles into a coarse dispersion of nonhydrated (phospho)lipids (hydrogenated soybean phosphatidylcholine and/or dicetylphosphate as charge...

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