Physiological importance of dehydroepiandrosterone

Dehydroepiandrosterone (DHEA), with its sulphate conjugate (DHEAS), is the most abundant steroid hormone in the circulation but its physiological importance is unclear. We propose that DHEA has either oestrogen-like or androgen-like effects depending on the hormonal milieu. In premenopausal women DH...

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Veröffentlicht in:	The Lancet (British edition) 1994-06, Vol.343 (8911), p.1479-1481
Hauptverfasser:	Eberling, P., Koivisto, V.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy & physiology Androgens Biological and medical sciences Breast Neoplasms - metabolism Cardiovascular diseases Cardiovascular Diseases - blood Dehydroepiandrosterone - blood Dehydroepiandrosterone - physiology Estrogens Female Fundamental and applied biological sciences. Psychology Health risks Humans Insulin Resistance - physiology Male Medical research Menopause - metabolism Metabolites Obesity - metabolism Physiology Reference Values Steroid hormones. Cholecalciferol derivatives Steroids Vertebrates: endocrinology
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