Characterization of Recombinant Mouse Perforin Expressed in Insect Cells Using the Baculovirus System

Perforin, a potent pore-forming protein, plays an important role in killer lymphocyte-mediated cytolysis. The studies on perforin, although already extensive, have been hampered by the limited amount of perforin naturally available from killer lymphocytes. In the present study, a full-length mouse p...

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Veröffentlicht in:	Biochemical and biophysical research communications 1994-05, Vol.201 (1), p.318-325
Hauptverfasser:	Liu, C.C., Persechini, P.M., Young, J.D.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Baculoviridae Biological Assay Calcium - metabolism Cell Compartmentation Hemolysis Membrane Glycoproteins - chemistry Membrane Glycoproteins - pharmacology Mice Molecular Weight Moths Perforin Pore Forming Cytotoxic Proteins Recombinant Proteins - chemistry
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