Impact of Metabolic Control of Diabetes During Pregnancy on Neonatal Hypocalcemia: A Randomized Study
OBJECTIVE: METHODS: RESULTS:Infants in the strict control group had a significantly lower rate of hypocalcemia (mean calcium less than 8.0 mg/dL in term infants and less than 7.0 mg/dL in preterm infants) than infants in the customary control group (17.6 versus 31.9%; P < .05). Using logistic reg...
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| Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1994-06, Vol.83 (6), p.918-922 |
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| container_title | Obstetrics and gynecology (New York. 1953) |
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| creator | DEMARINI, SERGIO MIMOUNI, FRANCIS TSANG, REGINALD C. KHOURY, JANE HERTZBERG, VICKI |
| description | OBJECTIVE:
METHODS:
RESULTS:Infants in the strict control group had a significantly lower rate of hypocalcemia (mean calcium less than 8.0 mg/dL in term infants and less than 7.0 mg/dL in preterm infants) than infants in the customary control group (17.6 versus 31.9%; P < .05). Using logistic regression analysis and after adjusting for the effects of gestational age, asphyxia, and White class on hypocalcemia, the difference between groups remained significant. The lowest infant serum calcium concentration correlated significantly with maternal glycohemoglobin A1 concentration at delivery (P = .03), gestational age (P = .0001), and the lowest serum magnesium concentration (P = .0001).
CONCLUSION:Strict management of diabetes in pregnancy is associated with a reduction in the rate of neonatal hypocalcemia. (Obstet Gynecol 1994;83:918-22) |
| doi_str_mv | 10.1097/00006250-199406000-00003 |
| format | Article |
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METHODS:
RESULTS:Infants in the strict control group had a significantly lower rate of hypocalcemia (mean calcium less than 8.0 mg/dL in term infants and less than 7.0 mg/dL in preterm infants) than infants in the customary control group (17.6 versus 31.9%; P < .05). Using logistic regression analysis and after adjusting for the effects of gestational age, asphyxia, and White class on hypocalcemia, the difference between groups remained significant. The lowest infant serum calcium concentration correlated significantly with maternal glycohemoglobin A1 concentration at delivery (P = .03), gestational age (P = .0001), and the lowest serum magnesium concentration (P = .0001).
CONCLUSION:Strict management of diabetes in pregnancy is associated with a reduction in the rate of neonatal hypocalcemia. (Obstet Gynecol 1994;83:918-22)</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>DOI: 10.1097/00006250-199406000-00003</identifier><identifier>PMID: 8190431</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: The American College of Obstetricians and Gynecologists</publisher><subject>Adult ; Biological and medical sciences ; Blood Glucose - analysis ; Diabetes Mellitus, Type 1 - blood ; Diabetes Mellitus, Type 1 - complications ; Diabetes Mellitus, Type 1 - therapy ; Diseases of mother, fetus and pregnancy ; Female ; Glycated Hemoglobin A - analysis ; Gynecology. Andrology. Obstetrics ; Humans ; Hypocalcemia - etiology ; Hypocalcemia - prevention & control ; Infant, Newborn ; Medical sciences ; Pregnancy ; Pregnancy in Diabetics - blood ; Pregnancy in Diabetics - therapy ; Pregnancy. Fetus. Placenta ; Risk Factors</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1994-06, Vol.83 (6), p.918-922</ispartof><rights>1994 The American College of Obstetricians and Gynecologists</rights><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4106312$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8190431$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DEMARINI, SERGIO</creatorcontrib><creatorcontrib>MIMOUNI, FRANCIS</creatorcontrib><creatorcontrib>TSANG, REGINALD C.</creatorcontrib><creatorcontrib>KHOURY, JANE</creatorcontrib><creatorcontrib>HERTZBERG, VICKI</creatorcontrib><title>Impact of Metabolic Control of Diabetes During Pregnancy on Neonatal Hypocalcemia: A Randomized Study</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>OBJECTIVE:
METHODS:
RESULTS:Infants in the strict control group had a significantly lower rate of hypocalcemia (mean calcium less than 8.0 mg/dL in term infants and less than 7.0 mg/dL in preterm infants) than infants in the customary control group (17.6 versus 31.9%; P < .05). Using logistic regression analysis and after adjusting for the effects of gestational age, asphyxia, and White class on hypocalcemia, the difference between groups remained significant. The lowest infant serum calcium concentration correlated significantly with maternal glycohemoglobin A1 concentration at delivery (P = .03), gestational age (P = .0001), and the lowest serum magnesium concentration (P = .0001).
CONCLUSION:Strict management of diabetes in pregnancy is associated with a reduction in the rate of neonatal hypocalcemia. (Obstet Gynecol 1994;83:918-22)</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - analysis</subject><subject>Diabetes Mellitus, Type 1 - blood</subject><subject>Diabetes Mellitus, Type 1 - complications</subject><subject>Diabetes Mellitus, Type 1 - therapy</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Female</subject><subject>Glycated Hemoglobin A - analysis</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Hypocalcemia - etiology</subject><subject>Hypocalcemia - prevention & control</subject><subject>Infant, Newborn</subject><subject>Medical sciences</subject><subject>Pregnancy</subject><subject>Pregnancy in Diabetics - blood</subject><subject>Pregnancy in Diabetics - therapy</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Risk Factors</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kV1vFCEUhonR1G31J5hwYbwbhWGGGbxrtmqb1I_4kXhHDsyhHWWGLTBp1l9f1l33Tm4I73leSB4IoZy95kx1b1hZsm5ZxZVqmCynaheJR2TF-05UtRA_H5MVY7Wqur5pnpLTlH4VgkslTshJzxVrBF8RvJo2YDMNjn7EDCb40dJ1mHMMfhdejGAwY6IXSxznG_ol4s0Ms93SMNNPGGbI4OnldhMseIvTCG_pOf0K8xCm8Q8O9Ftehu0z8sSBT_j8sJ-RH-_ffV9fVtefP1ytz68rK2olKikM5xY6NF2PDoSworNqUJ2sa5CNbQx3vK1b2RYJg5OGmR56acSgwKnOiTPyan_vJoa7BVPW05gseg8zhiXprjR5y0QB-z1oY0gpotObOE4Qt5ozvTOs_xnWR8N_o131xeGNxUw4HIsHpWX-8jCHVJy4WGyN6Yg1nEnB64I1e-w--Iwx_fbLPUZ9i-Dzrf7f_4oHgd-SaA</recordid><startdate>199406</startdate><enddate>199406</enddate><creator>DEMARINI, SERGIO</creator><creator>MIMOUNI, FRANCIS</creator><creator>TSANG, REGINALD C.</creator><creator>KHOURY, JANE</creator><creator>HERTZBERG, VICKI</creator><general>The American College of Obstetricians and Gynecologists</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199406</creationdate><title>Impact of Metabolic Control of Diabetes During Pregnancy on Neonatal Hypocalcemia: A Randomized Study</title><author>DEMARINI, SERGIO ; MIMOUNI, FRANCIS ; TSANG, REGINALD C. ; KHOURY, JANE ; HERTZBERG, VICKI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3293-63b11ca7eb78efa33c37c9d97622a64c4b1f152565109df6b0b8a86b3d9af97f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose - analysis</topic><topic>Diabetes Mellitus, Type 1 - blood</topic><topic>Diabetes Mellitus, Type 1 - complications</topic><topic>Diabetes Mellitus, Type 1 - therapy</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Female</topic><topic>Glycated Hemoglobin A - analysis</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Hypocalcemia - etiology</topic><topic>Hypocalcemia - prevention & control</topic><topic>Infant, Newborn</topic><topic>Medical sciences</topic><topic>Pregnancy</topic><topic>Pregnancy in Diabetics - blood</topic><topic>Pregnancy in Diabetics - therapy</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DEMARINI, SERGIO</creatorcontrib><creatorcontrib>MIMOUNI, FRANCIS</creatorcontrib><creatorcontrib>TSANG, REGINALD C.</creatorcontrib><creatorcontrib>KHOURY, JANE</creatorcontrib><creatorcontrib>HERTZBERG, VICKI</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DEMARINI, SERGIO</au><au>MIMOUNI, FRANCIS</au><au>TSANG, REGINALD C.</au><au>KHOURY, JANE</au><au>HERTZBERG, VICKI</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of Metabolic Control of Diabetes During Pregnancy on Neonatal Hypocalcemia: A Randomized Study</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1994-06</date><risdate>1994</risdate><volume>83</volume><issue>6</issue><spage>918</spage><epage>922</epage><pages>918-922</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>OBJECTIVE:
METHODS:
RESULTS:Infants in the strict control group had a significantly lower rate of hypocalcemia (mean calcium less than 8.0 mg/dL in term infants and less than 7.0 mg/dL in preterm infants) than infants in the customary control group (17.6 versus 31.9%; P < .05). Using logistic regression analysis and after adjusting for the effects of gestational age, asphyxia, and White class on hypocalcemia, the difference between groups remained significant. The lowest infant serum calcium concentration correlated significantly with maternal glycohemoglobin A1 concentration at delivery (P = .03), gestational age (P = .0001), and the lowest serum magnesium concentration (P = .0001).
CONCLUSION:Strict management of diabetes in pregnancy is associated with a reduction in the rate of neonatal hypocalcemia. (Obstet Gynecol 1994;83:918-22)</abstract><cop>New York, NY</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>8190431</pmid><doi>10.1097/00006250-199406000-00003</doi><tpages>5</tpages></addata></record> |
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| ispartof | Obstetrics and gynecology (New York. 1953), 1994-06, Vol.83 (6), p.918-922 |
| issn | 0029-7844 1873-233X |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Biological and medical sciences Blood Glucose - analysis Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - therapy Diseases of mother, fetus and pregnancy Female Glycated Hemoglobin A - analysis Gynecology. Andrology. Obstetrics Humans Hypocalcemia - etiology Hypocalcemia - prevention & control Infant, Newborn Medical sciences Pregnancy Pregnancy in Diabetics - blood Pregnancy in Diabetics - therapy Pregnancy. Fetus. Placenta Risk Factors |
| title | Impact of Metabolic Control of Diabetes During Pregnancy on Neonatal Hypocalcemia: A Randomized Study |
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