Isolation and characterization of the aspartokinase and aspartate semialdehyde dehydrogenase operon from mycobacteria

Summary Diaminopimelic acid (DAP) is a major component of the peptidoglycan layer of the mycobacterial cell wall. The mycobacterial cell wall has been implicated as a potential virulence factor and is highly immunogenic. The pathway for biosynthesis of DAP may serve as a target in the design of anti...

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Veröffentlicht in:	Molecular microbiology 1994-02, Vol.11 (4), p.629-639
Hauptverfasser:	Cirillo, Jeffrey D., Weisbrod, Torin R., Pascopella, Lisa, Bloom, Barry R., Jacobs, William R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Aspartate Kinase - genetics Aspartate-Semialdehyde Dehydrogenase - genetics Bacterial Proteins - genetics Bacteriology Base Sequence Biological and medical sciences Consensus Sequence Diaminopimelic Acid - metabolism Escherichia coli - genetics Fundamental and applied biological sciences. Psychology Genes, Bacterial Genetic Complementation Test Metabolism. Enzymes Microbiology Molecular Sequence Data Mycobacterium - enzymology Mycobacterium - genetics Mycobacterium avium Mycobacterium smegmatis Mycobacterium tuberculosis Open Reading Frames Operon Sequence Alignment Sequence Homology, Amino Acid
Online-Zugang:	Volltext
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