A microdialysis study of amino acid concentrations in the extracellular fluid of the substantia nigra of freely behaving GEPR-9s: relationship to seizure predisposition

Substantia nigra (SN) is known to play an important role in seizure generalization. Both excitatory and inhibitory neurotransmitters can modulate this role of SN. Previous studies have shown that GABA as well as aspartate and glutamate participate in seizure regulation through this site. Evidence fo...

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Veröffentlicht in:	Epilepsy research 1994-02, Vol.17 (2), p.157-165
Hauptverfasser:	Doretto, M.C., Burger, R.L., Mishra, P.K., Garcia-Cairasco, N., Dailey, J.W., Jobe, P.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - metabolism Animals Biological and medical sciences Chromatography, High Pressure Liquid Convulsions Epilepsy - genetics Epilepsy - metabolism Extracellular Space - metabolism GABA Genetically epilepsy-prone rats (GEPRs) Glutamate Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Male Medical sciences Microdialysis Nervous system (semeiology, syndromes) Neurology Potassium - pharmacology Rats Rats, Inbred Strains Seizures Seizures - physiopathology Spectrophotometry, Ultraviolet Substantia nigra Substantia Nigra - anatomy & histology Substantia Nigra - metabolism Taurine - metabolism
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